Screening of osteoporosis using 3D fractal dimension analysis of trabecular pattern in the dental radiogram

使用牙科放射照片中小梁模式的 3D 分形维数分析筛查骨质疏松症

• 批准号: 07672039
• 负责人: HONDA Eiichi
• 金额: $ 1.54万
• 依托单位: Tokyo Medical and Dental University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 1995
• 资助国家: 日本
• 起止时间: 1995 至 1997
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-07672039/
• 关键词: Fractal Dimension; Lumber Bone Mineral Density; Mandibular Bone Mineral Density; Dental Radiogram; CT; 骨粗鬆症; 骨ミネラル; 下顎骨

Improving pixel dilation method which is developed as a measurement method of 2D fractal dimension, the authors developed modified pixel dilation method which is more accurate method of measurement of fractal dimension. We spread the 2D method to 3D method and could measure 3D fractal dimension of the trabecular pattern of the mandibular bone in dental radiograms using the 3D method. The 3D method, boxel dilation method, can make it possible to measure the 3D fractal dimension. It was ascertained that the measurement accuracy was enough. Fractal analysis of the trabecular pattern using the boxel dilation method makes it possible to analyze the bone mineral density and it was possible to improve the accuracy of the measurement by deleting the noise in the dental radiogram.In the present study, the bone mineral density of the mandibular bone in the patients who was suspected osteoporosis didn't reflect the bone mineral density in the body (lumber mineral density) so that we couldn't make different diagnosis of osteoporosis. However, it was possible to estimate the bone mineral density using the fractal analysis of the region reflecting the whole bone mineral density and the present method is expected to be convenient and sensitive method for early diagnosis of osteoporosis.

对二维分形维数的测量方法像素膨胀法进行了改进，提出了一种更精确的测量分形维数的方法--改进像素膨胀法。我们将二维方法推广到三维方法，利用三维方法可以测量下颌骨骨小梁结构的三维分形维数。三维分形维数的测量方法，即盒格膨胀法，使三维分形维数的测量成为可能。确定测量精度足够。使用Boxel扩张方法对骨小梁图案进行分形分析使得分析骨矿物质密度成为可能，并且可以通过删除牙科X线照片中的噪声来提高测量的准确性。可疑骨质疏松患者下颌骨骨骨密度不能反映全身骨密度（腰椎矿物质密度），使我们不能作出不同的诊断骨质疏松症。然而，它是可能的估计骨密度使用反映整个骨密度的区域的分形分析，本方法有望成为一种方便和敏感的方法，用于骨质疏松症的早期诊断。

项目成果

土門正治、誉田栄一他: "CT画像データによる椎骨骨梁構造のフラクタル次元測定法" 歯科放射線. 37. 118 (1997)

Masaharu Domon、Eiichi Honda 等：“使用 CT 图像数据的椎骨小梁骨结构的分形维数测量方法”《牙科放射学》37. 118 (1997)。

M Domon, E Honda, T sasaki: "A method to measure fractal dimensions of vertebral microstructures by using CT image deta" Dental Radiology. vol37. 118 (1997)

M Domon、E Honda、T sasaki：“一种使用 CT 图像数据测量椎骨微结构分形维数的方法”牙科放射学。

K Bando, H Nittal, M Matsubara, E Honda et al.: "Mandibular BMD in Periodonatally Healthy and Edentulous Postmenopausal Women" J Dent Res. vol77. 923 (1998)

K Bando、H Nittal、M Matsubara、E Honda 等人：“牙周健康和无牙绝经后妇女的下颌 BMD”J Dent Res。

M Domon, E Honda, T sasaki: "Tow dimensional images of fractal sets and their usefulness in analysis of the methods of dimension measurement" Computer Assisted Radiology and Surgery Proceedings of the 12th International Symposium and Exhibition. 972 (1998

M Domon、E Honda、T sasaki：“分形集的二维图像及其在维度测量方法分析中的有用性”第 12 届国际研讨会和展览的计算机辅助放射学和外科手术记录。

土門正治、誉田栄一、佐々木武仁: "CT画像データによる椎骨骨梁構造のフラクタル次元測定法" 歯科放射線. 37巻増刊号. 118- (1997)

Masaharu Domon、Eiichi Honda、Takehito Sasaki：“使用 CT 图像数据的椎骨小梁骨结构的分形维数测量方法”《牙科放射学》第 37 卷特刊。