Creation of non-magnetism stent and aneurysm clip for high magnetic field MR imaging

创建用于高磁场磁共振成像的非磁性支架和动脉瘤夹

• 批准号: 23592767
• 负责人: HONDA Eiichi
• 金额: $ 2.58万
• 依托单位: The University of Tokushima
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2011
• 资助国家: 日本
• 起止时间: 2011 至 2013
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23592767/
• 关键词: 磁化率; Au-Pt-Nb合金; MR画像; 非磁性合金; 生体内金属; ステント; 脳動脈瘤クリップ; 脳血管クリップ; 血管内ステント; MRI; 非磁性; ３元系合金

A three component alloy was developed by adding a new metallic element based on an Au-Pt alloy made by the previous study. Firstly, new metallic elements, Nb, Ir, Hf and Ta were selected. After that Ir, Hf and Ta were excluded because the alloys added the element showed an obvious a metallic artifact in MR imaging. Concerning to an alloy added Nb, it was shown a metallic artifact was hardly seen in MR imaging according to the content. The content of Pt and Nb was changed and the improvement of a mechanical characteristic was tried by the difference of the heat-treatment method. It was concluded that Au-7Nb-5Pt alloy was optimum for aneurysm clip and stent.

在金铂合金的基础上添加一种新的金属元素，研制出一种三元合金。 首先，选择了新的金属元素Nb、Ir、Hf和Ta。 之后，Ir、Hf和Ta被排除，因为添加该元素的合金在MR成像中显示出明显的金属伪影。对于添加Nb的合金，根据含量，在MR成像中几乎看不到金属伪影。改变Pt和Nb的含量，并通过热处理方法的不同来尝试机械特性的改善。结论：Au-7 Nb-5 Pt合金是最佳的动脉瘤夹和支架材料。

项目成果

Magnetic susceptibility and hardness of Au-xPt-yNb alloys for biomedical applications

用于生物医学应用的 Au-xPt-yNb 合金的磁化率和硬度

• DOI: 10.1016/j.actbio.2013.05.028
• 发表时间: 2013
• 期刊: Acta Biomaterialia
• 影响因子: 9.7
• 作者: Emi Uyama;Shihoko Inui;Kenichi Hamada;Eiichi Honda;Kenzo Asaoka
• 通讯作者: Kenzo Asaoka

歯科における磁気用途の将来MRI対応生体内金属の開発

开发未来 MRI 兼容的体内金属，用于牙科磁性应用

• 发表时间: 2013
• 期刊: 日本磁気歯科学会雑誌
• 作者: 誉田栄一;浜田賢一;倉林亨;宇山恵美;吉田みどり
• 通讯作者: 吉田みどり