Relationship between the motoneuron pool excitability in the resting state and its amount of change during the voiuntary movement in man

人静息状态运动神经元池兴奋性与其随意运动时变化量的关系

• 批准号: 07680126
• 负责人: FUNASE Kozo
• 金额: $ 1.41万
• 依托单位: School of Allied Medical Sciences, Nagasaki University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 1995
• 资助国家: 日本
• 起止时间: 1995 至 1996
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-07680126/
• 关键词: Motoneuron pool excitability; H-reflex; Voluntary movement; Reciprocal inhibition; Presynaptic inhibition

We examined the relationship between the amount of natural reciprocal inhibition during dorsiflexion exerted at 10%, 30%, and 50% of maximal voluntary contraction (MVC) on the soleus motoneuron (MN) pool excitability of several normal subjects and their MN pool excitability in the resting state. During dorsiflexion at 10% and 30% of MVC,the inhibitory effects were decreased with increasing MN pool excitability. On the other hand, amount of presynaptic inhibition of the soleus MNs in the resting state, as assessed by vibration of the Achilles tendon, was greater in subjects with lower MN pool excitability in the resting state. These observations suggest that the decrease in MN pool excitability induced by natural reciprocal inhibition during dorsiflexion is predominantly dependent on the differences in level of presynaptic inhibition which affect MN pool excitability in the resting state.

我们研究了几名正常人在背屈时对比目鱼肌运动神经元(MN)池兴奋性施加的最大自愿收缩(MVC)10%、30%和50%的自然相互抑制量与他们静息状态下MN池兴奋性的关系。在背屈时，MVC的10%和30%时，抑制效应随MN池兴奋性的增加而减弱。另一方面，通过跟腱振动来评估静息状态下比目鱼肌MNS的突触前抑制量，在静息状态下MN池兴奋性较低的受试者中，突触前抑制程度更大。这些观察结果表明，背屈运动中自然的相互抑制引起的MN池兴奋性的降低主要依赖于突触前抑制水平的不同，而突触前抑制水平的不同影响了MN池在静息状态下的兴奋性。

项目成果

Nishihira Y,Araki H,Funase K,Imanaka K et al: "Somatosensory evoked potentials following voluntary movement during upper arm compression" Electromyogr Clin Neurophysiol. 36. 21-28 (1996)

Nishihira Y、Araki H、Funase K、Imanaka K 等人：“上臂压缩期间随意运动后的体感诱发电位”Electromyogr Clin Neurophysicalol。

Funase K,Imanaka K,Nishihira Y: "Inhibition of the soleus H-reflex during dorsiflexion on individual differences in maxmal soleus H-reflex as a test reflex" Perceputual and Motor Skills. (in press).

Funase K、Imanaka K、Nishihira Y：“背屈时比目鱼肌 H 反射的抑制对最大比目鱼肌 H 反射的个体差异作为测试反射”知觉和运动技能。

Funase K et al: "Evident difference in the excitability of the motoneuron pool between normal subjects and spastic patients with spasticity assessed by a new method using H-reflex and M-response" Neuroscience Letters. 203. 127-130 (1996)

Funase K 等人：“通过使用 H 反射和 M 反应的新方法评估正常受试者和痉挛患者之间运动神经元池的兴奋性存在明显差异”《神经科学快报》。

Nishihira Y et al: "Modification of central sensory-motor system in different sensory interferences tasks" Advances in Exercise and Sports Physiology. 2. 57-64 (1996)

Nishihira Y 等人：“不同感觉干扰任务中中枢感觉运动系统的修改”运动和运动生理学进展。

Funase K,Imanaka K.Nishihira Y,Higashi T,Yoshimura T,Araki H: "Soleus motoneuron pool excitability in the resting state affects the amount of reciprocal inhibition during dorsiflexion" Adv Exerc Sports Physiol. 2. 65-52 (1996)

Funase K，Imanaka K.Nishihira Y，Higashi T，Yoshimura T，Araki H：“静息状态下的比目鱼肌运动神经元池兴奋性影响背屈期间的相互抑制量”Adv Exerc Sports Physiol。