Space, time and boundary conditions: Mathematics for evolving plaques.

空间、时间和边界条件：演化斑块的数学。

• 批准号: DP220101454
• 负责人: Prof Mary Myerscough
• 金额: $ 30.34万
• 依托单位: The University of Sydney
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2022
• 资助国家: 澳大利亚
• 起止时间: 2022-09-01 至 2025-08-31
• 项目状态: 未结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP220101454
• 关键词: Space; time; boundary; conditions; Mathematics

This project aims to create new mathematical theory to model the morphology of atherosclerotic plaques, which cause heart attacks and strokes, as plaques grow or regress. The project expects to devise new mathematical tools for formulating novel spatial models for cellular processes inside the plaque. These should give a new window into plaque growth and spatial structures . Expected outcomes include powerful and reliable mathematical models, new tools to understand plaque evolution, and national and international collaborations with scientists and mathematicians. This should provide significant benefits including increased capacity to use mathematical models in vascular biology and training young researchers in interdisciplinary methods.

该项目旨在创建新的数学理论来模拟动脉粥样硬化斑块的形态，这些斑块会导致心脏病发作和中风，因为斑块会生长或消退。该项目希望设计新的数学工具，为斑块内的细胞过程制定新的空间模型。这将为斑块生长和空间结构提供一个新的窗口。预期成果包括强大而可靠的数学模型，了解斑块演变的新工具，以及与科学家和数学家的国家和国际合作。这将提供显着的好处，包括提高能力，使用数学模型在血管生物学和培训年轻的研究人员在跨学科的方法。