New mathematics for lipids and cells: structured models for atherosclerosis

脂质和细胞的新数学：动脉粥样硬化的结构化模型

• 批准号: DP200102071
• 负责人: Prof Mary Myerscough
• 金额: $ 35.12万
• 依托单位: The University of Sydney
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2020
• 资助国家: 澳大利亚
• 起止时间: 2020-01-01 至 2024-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP200102071
• 关键词: New; mathematics; lipids; cells; structured

The project aims to create new mathematical theory for immune cell behaviour which leads to heart attacks and strokes. This includes formulation and analysis of new types of mathematical models for atherosclerotic plaque development, leading to the creation of new mathematical tools to investigate cell fate in plaques and to generate new hypotheses for experimental research. Expected outcomes of this project include powerful and reliable mathematical models ready for application, and national and international collaborations with scientists and mathematicians. This should provide significant benefits including increased capacity to use mathematical models in vascular biology and training young researchers in interdisciplinary methods.

该项目旨在为导致心脏病发作和中风的免疫细胞行为创造新的数学理论。这包括制定和分析动脉粥样硬化斑块发展的新型数学模型，导致创建新的数学工具来研究斑块中的细胞命运，并为实验研究产生新的假设。 该项目的预期成果包括可供应用的强大而可靠的数学模型，以及与科学家和数学家的国家和国际合作。 这将提供显着的好处，包括提高能力，使用数学模型在血管生物学和培训年轻的研究人员在跨学科的方法。