Actin myosin system and nanomachine using thermal noise
Actin myosin system and nanomachine using thermal noise
批准号:
08558095
负责人:
MATSUURA Horoyuki
金额:
$3.46万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
1996
资助国家:
日本
项目状态:
已结题
起止时间:
1996 至 1997
中文摘要
为了理解肌动蛋白-肌球蛋白系统在肌肉中的运动,提出了随机斜杆模型(SIRM)。SIRM有许多像肌凝蛋白一样从身体上突出的倾斜杆,每当这些杆独立振动时,SIRM总是向一个方向前进。SIRM利用随机共振和随机开场中的倾斜杆将热噪声转换为单向运动。我们具体估计了SIRM作为肌动蛋白-肌球蛋白系统的概念模型的物理特性。如果SIRM的半径为r=5nm,质量为10E-21kg,则估计其随机共振频率接近声子频率10E11rad/s。随机共振振幅为2*10E-11m。此外,该机的物理功约为10e - 18焦耳,几乎等于1ATP水解的能量,产量为10E-10N/头。因此,我们认为肌动蛋白-肌球蛋白系统是利用水分子的随机运动来运动的。
英文摘要
Stochastic Inclined Rods Model (SIRM) is proposed for understanding the movement of actin myosin system in muscle. SIRM has many inclined rods stood out from its body like myosin, and it moves always forward to one direction whenever those rods are independently vibrating. SIRM can convert the thermal noise to the one directional motion by using stochastic resonance and inclined rods in random open fields. We estimate concretely the physical characteristics of SIRM as a conceptual model of actin myosin system. If SIRM have the radius r=5nm and mass 10E-21kg like a myosin molecule, the estimated frequency of stochastic resonance which is nearly phonon frequency 10E11rad/s. The amplitude of stochastic resonance is 2*10E-11m. Moreover, physicalwork of this machine is bout 10E-18joules, which is nearly equal to the energy of 1ATP hydrolysis, and output is 10E-10N/head. As a conclusion, we point out that actin myosin system in muscle utilizing the random motion of water molecules for its movement.
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HIROYUKI Matsuura: "On Energy Conversion on Muscle and Artificial Muscle" Jr.of artificial Organ. 19 (9). 551 (1996)
HIROYUKI Matsuura:《论肌肉和人工肌肉的能量转换》Jr.of Artificial Organ。
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松浦弘幸: "パ・リティ 11月号" 丸善出版, 13 (1996)
松浦博之:《Pa Liti 11月号》丸善出版社,13(1996)
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Matsuura H, Nakano M: "Theoretioal Appreach to Actin Myosin as system as an exanple of Compex system" Jr.of Biomed.Fuzzyand Human Suance. 3(1). 47-52 (1997)
Matsuura H、Nakano M:“以肌动蛋白肌球蛋白作为复合系统示例的理论方法”Jr.of Biomed.Fuzzyand Human Suance。
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Matsuura H: "Stochastic resonance in artificial muscule" ASAIO Journal. 42(2). 56 (1996)
Matsuura H:“人造肌肉中的随机共振”ASAIO 杂志。
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HROYUKI Matsuura: "Weak non-linear solution of Langevin equation and stochastic resonance" Meeting of the physical Society of Japan. part3. 699 (1996)
HROYUKI Matsuura:“朗之万方程的弱非线性解和随机共振”日本物理学会会议。
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