The Effects of Day Treatment on Disabilities and Relapse Prevention of schizophrenia.

我们的假设是，日间治疗配合最佳的药物治疗可以改善精神分裂症的致残率和复发率，从而使长期预后更好。1996年，我们与我们的研究项目合作，对7个日间治疗中心和8个社区工作坊的工作人员进行了评估培训。在1997年1月至1998年12月期间，我们为这些设施登记了新的管理员。现在我们对80名注册服务员进行了为期两年的跟踪调查。1、对象：80名注册服务员被他们的精神科医生诊断为精神分裂症。52例为男性。平均年龄33.8岁。精神分裂症的平均发病年龄为24.0岁。方法：在两年的时间里，我们对受试者进行了四次评估：(1)在日间治疗中心或社区车间开始治疗时，(2)开始治疗半年后，(3)一年后，(4)两年后，以L…为评估工具更多精神疾病生活事件评定量表(LASMI)、简明精神病评定量表(BPRS)、WHO-QOL量表和全球评定量表(GAS)。3、结果和讨论：我们只对1/3的受试者完成了为期一年的随访研究，目前我们正在继续随访研究。因此，我们在起始点(n=80)、半年后(n=31)和一年后(n=21)报告了结果。在人口学特征、LAMI、GAS和WHO-QOL方面，日间治疗组和社区工作坊组之间没有显著差异。半年后，日间治疗组Lasmi的耐力/稳定性分量表较开始时有显著改善，而Lasmi的人际关系分量表和工作分量表得分显著高于社区工作坊组。LSAMI的日常生活分量表的改善与WHO-QOL的心理分量表的改善显著相关。一年后，日间治疗组的Lasmi日常生活量表评分较治疗前有显著改善。我们的结论是，随着主观生活质量的改变，日间治疗可以改善精神分裂症患者的某些残疾成分(即稳定性和日常生活能力)。较少

Our hypothesis is that day treatment with optimal pharmacotherapy can improve disabilities and relapse rate of schizophrenia which will lead long term prognosis to be better. We had practiced training of evaluation for staff of seven day treatment centers and eight community workshops which co-operated with our research project in 1996. We registered new attendants of these facilities from January 1997 to December 1998. Now we are following 80 registered attendants for two years.1, Subjects: 80 registered attendants were diagnosed with schizophrenia by their psychiatrists. Fifty-two cases were male. The average age was 33.8 year old. The average age of onset of schizophrenia was 24.0 year old. The average umber of previous hospitalization was 1.9.2, Method: We evaluated subjects four times for two years: (1) at the start of the treatment of day treatment centers or community workshops, (2) half year from the start, (3) one year later, (4) two years later, Evaluation measures were the L … More ife Assessment Scale for persons with Mental Illness (LASMI), the Brief Psychiatric Rating Scale (BPRS), the WHO-QOL scale, and the Global Assessment Scale (GAS).3, Results and Discussion: We have finished one-year follow up study only in 1/3 subjects, and we are now continuing follow-up study. Thus we reported results at the start point (n=80), half-year later (n=31), and one-year later (n=21). There was no significant difference of demographic features, LASMI, GAS, and WHO-QOL between the day treatment group and the community workshops group. At the point of half year later, the day treatment group showed significant improvement of Endurance/Stability subscale of LASMI than at the start point, and significant better score of Interpersonal relationship subscale and Work subscale of LASMI than the community workshops group. There was significant correlation between improvement of Daily living subscale of LSAMI and improvement of psychological subscale of WHO-QOL. At the point of one year later, the day treatment group showed significant improvement of Daily living subscale of LASMI than at the start point. Our conclusion was that some components of disabilities of schizophrenia (I.e. stability and daily living skills) could be improved by day treatment with change of subjective QOL. Less