The course of cognitive functioning of first episode schizophrenia and effects of cognitive rehabilitation

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Cognitive impairment of first episode schizophrenia was followed prospectively and cross-sectional to clarify time course and influence of cognitive functioning on psychiatric symptoms and social functioning. Twelve schizophrenia diagnosed with DSM IV were evaluated at baseline, after 6 months, and after 1 year using with BACS-J, PANSS, LSP, and GAF. Verbal memory, motor speed, and executive functioning were significantly improved after 1 year. Social relationship, communication skills, and GAF also significantly improved after 1 year. Nineteen first episode schizophrenia (after 6 month follow up point) were compared with 18 schizophrenia (DSM-IV) who were speculated that onset was 5 years ago. Five years group were significantly better in verbal fluency, social relationship, and general pathology than first episode group. Five years group were significantly worse in verbal memory and executive functioning.