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Continuing monitaring and manegement of natural environment on wildlife pathobiology and ecology.

持续监测和管理野生动物病理学和生态学方面的自然环境。

基本信息

批准号：
10306020
负责人：
MASEGI Toshiaki
金额：
$ 23.49万
依托单位：
GIFU UNIVERSITY
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (A).
财政年份：
1998
资助国家：
日本
起止时间：
1998 至 2000
项目状态：
已结题

项目摘要

1. To clarify the infectivity of parapox virus re-emerging in Japanese serow in mountains was inoculated to sheep. As a result, parapox virus was proved to spread from serow to sheep easily. This study warns the role of serow as a reservoir in parapox virus infection.2. GHV-1 is a new type emerging equine herpesvirus isolated from a mass outbreak of encephalitis in gazelles. In this study, GHV-1 was designated as EHV-9 based on virological and pathological studies. EHV-9 induced experimentally encephalitis in wide variety of animals including horses, goats, cattle, pigs, dogs, hamsters, mice and guinea pigs. This virus was fatal to all animals infected except horses, cattle and pigs. EHV-9 was shown to be strongly neurotropic virus, which had an intense infectivity to a wide range of animals.3. The resudue levels of several organochlorine compounds, including PCBs, DDTs, HCH, were determined in samples of various wildlife living in Chubu district, central part of Japan. As a result, high residue levels of organochlorine compounds were detected in birds, especially raptors, which were higher than those in other mammals. Besides, influences of compounds on physical condition in animals were investigated experimentally.4. In this study, useful information for conservation of endangered wildlife was obtained. Ecological and physiological condition of reproduction in Japanese bears and Northern seals was investigated. In addition, establishment of techniques for artificial reproduction in endangered wildlife was done. Furthermore, some useful information on the endocrine disruptor accumulation and reproductive disorder in mammals and raptors was obtained. These results indicate that continuing monitoring of natural environment is needed to protect the earth. On the other hand, research on wild birds pathology, zoo animal pathology including non-human primates and mechanism of hibernation etc. were done.

1.为明确山区日本血清中再次出现的副痘病毒的感染性，将其接种绵羊。结果表明，副痘病毒很容易从血清传播到绵羊。这项研究警告了血清作为副痘病毒感染的储存库的作用。GHV-1是从一次瞪羚脑炎大规模暴发中分离到的一种新型马疱疹病毒。在本研究中，根据病毒学和病理学研究，GHV-1被指定为EHV-9。EHV-9在包括马、山羊、牛、猪、狗、仓鼠、小鼠和豚鼠在内的多种动物中诱导实验性脑炎。这种病毒对除马、牛和猪以外的所有受感染动物都是致命的。EHV-9是一种嗜神经性强的病毒，对多种动物具有强烈的感染性.测定了日本中部地区多种野生动物样品中多氯联苯（PCBs）、滴滴涕（DDTs）、六六六（HCH）的残留水平。因此，在鸟类，特别是猛禽体内检测到了高水平的有机氯化合物残留，高于其他哺乳动物。此外，还通过动物实验研究了化合物对动物身体状况的影响.本研究为濒危野生动物的保护提供了有益的信息。本文对日本熊和北方海豹的繁殖生理生态条件进行了研究。此外，还建立了濒危野生动物的人工繁殖技术。此外，还获得了一些有关内分泌干扰物在哺乳动物和猛禽中积累和生殖障碍的有用信息。这些结果表明，需要继续监测自然环境，以保护地球。另一方面，开展了野生鸟类病理学、动物园动物病理学（包括非人灵长类动物）和冬眠机理等方面的研究。