Initial solubility and durability of polymeric calcium phosphate cements

聚合磷酸钙骨水泥的初始溶解度和耐久性

• 批准号: 10671792
• 负责人: MATSUYA Yoko
• 金额: $ 2.11万
• 依托单位: KYUSHU UNIVERSITY
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 1998
• 资助国家: 日本
• 起止时间: 1998 至 1999
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-10671792/
• 关键词: tetracalcium phosphate; poly (methyl vinyl ether-maleic acid); poly (acrylic acid); cement; hydroxyapatite; α-tricalcium phosphate cements; initial solubility; durability; α-リン酸3カルシウム

Mechanical strength and in vitro durability of four experimental and two commercial calcium phosphate dental cements were assessed. Hydroxyapatite formation processes in these calcium phosphate cements were also examined by means of x-ray diffraction analysis and their relationship with mechanical strength was discussed. The hydroxyapatite-forming polymeric calcium phosphate cements prepared from medium and fine tetracalcium phosphate powder and poly (methyl vinyl ether-maleic acid) showed lower compressive strength and higher flexural strength than the teracalcium phosphate cement prepared using poly (acrylic acid) and non hydroxyapatite-forming commercial α-tricalcium phosphate cements. The hydroxyapatite formation seemed to correspond to lowering in compressive strength of the cements based on tetracalcium phosphate and poly (methyl vinyl ether-maleic acid), while, in the case of the cement based on tetracalcium phosphate and poly (acrylic acid), no relationship was observed between the hydroxyapatite formation and the compressive strength. The hydroxyapatite-forming polymeric cements prepared using finely ground tetracalcium phosphate powder showed enhanced strength, even after prolonged immersion in water, compared to similar cements derived from the large sized tetracalcium phosphate. Initial solubility of both the experimental polymeric calcium phosphate cements seemed to be lower than that of the commercial calcium phosphate cements, which were prepared using organic acids.

对四种实验性和两种商业磷酸钙牙科水泥的机械​​强度和体外耐久性进行了评估。还通过 X 射线衍射分析检查了这些磷酸钙水泥中羟基磷灰石的形成过程，并讨论了它们与机械强度的关系。由中细磷酸四钙粉和聚甲基乙烯基醚-马来酸制备的形成羟基磷灰石的聚合磷酸钙骨水泥比使用聚丙烯酸和非羟基磷灰石形成的商业α-磷酸三钙骨水泥制备的磷酸四钙骨水泥表现出较低的抗压强度和较高的弯曲强度。羟基磷灰石的形成似乎与基于磷酸四钙和聚(甲基乙烯基醚-马来酸)的水泥的抗压强度的降低相对应，而在基于磷酸四钙和聚(丙烯酸)的水泥的情况下，没有观察到羟基磷灰石的形成和抗压强度之间的关系。与由大尺寸磷酸四钙衍生的类似水泥相比，使用精细研磨的磷酸四钙粉末制备的形成羟基磷灰石的聚合物水泥即使在长时间浸泡在水中后也显示出增强的强度。两种实验聚合磷酸钙水泥的初始溶解度似乎都低于使用有机酸制备的商业磷酸钙水泥的初始溶解度。

项目成果

Matsuya Y., Matsuya S., Antonucci J. M., Takagi S., Chow L. C., Akamine A.: "Effect of powder grinding on hydroxyapatite formation in a polymeric calcium phosphate cement prepared from tetracalcium phosphate and poly (methyl vinyl ether-maleic acid)"Bioma

Matsuya Y.、Matsuya S.、Antonucci J. M.、Takagi S.、Chow L.C.、Akamine A.：“粉末研磨对由磷酸四钙和聚（甲基乙烯基醚-马来酸）制备的聚合磷酸钙水泥中羟基磷灰石形成的影响

Matsuya S., Matsuya Y., Takagi S., Chow L. C.: "Effect of fluoride on apatite formation from CaィイD24ィエD2(POィイD24ィエD2)ィイD22ィエD2O in 0.1 mol LィイD1-1ィエD1 KHィイD22ィエD2POィイD24ィエD2"J Materials Science : Materials in Medicine. 9. 325-331 (1998)

Matsuya S.、Matsuya Y.、Takagi S.、Chow L.C.：“氟化物对 0.1 mol Li D1-1 D1 KH D22 D2PO D24 D2 中 CaD24D2(POD24D2)D22D2O 形成磷灰石的影响”J 材料科学：医学材料。 9. 325-331 (1998)

Akashi A: "The relationship between water absorption characteristics and the mechanical strength of resin-modified glass-ionomer cements in long-term water storage"Biomaterials. 20. 1573-1578 (1999)

明石A：“长期储水的树脂改性玻璃离子水门汀吸水特性与机械强度的关系”生物材料。

Matsuya S.: "Effect of fluoride on apatite formation from Ca_4(PO_4)_2O in 0.1mol L^<-1> KH_2PO_4"J Materials Science: Materials in Medicine. 9. 325-331 (1998)

Matsuya S.：“0.1mol L^<-1> KH_2PO_4 中氟化物对 Ca_4(PO_4)_2O 形成磷灰石的影响”J 材料科学：医学材料。

明石 あかね: "光硬化型グラスアイオノマーセメントの吸水について"日本歯科保存学雑誌. 41・3. 565-571 (1998)

Akane Akashi：“关于光固化玻璃离子水门汀的吸水率”日本保守牙科杂志 41・3（1998 年）。