Analysis of the motor unit action potentials in patients with myofascial pain

为了比较肌筋膜疼痛患者和无症状对照者在次最大随意收缩水平下咬肌中运动直到动作电位（MUAP）的构型和放电特性，并评估肌筋膜疼痛是否具有在神经肌肉疾病中观察到的异常肌电特性，我进行了以下四个实验：（1）本研究首先探讨了用每秒转数（TS）和每转振幅（AT）结合表面电极作为咀嚼肌功能评价方法的可行性，结果表明：在所有收缩水平下，AT均随收缩而增加，证明了线性关系，而TS显示出非线性增加，其特征在于初始急剧上升，然后是平台，这是用第三多项式函数模拟的。我们认为，TS和AT可能提供有价值的生理信息的潜在机制的招聘， ...更多信息 （2）第二，我们尝试证明利用肌电分解系统（ADEMG）作为一种手段的可行性，使用同心针电极在无症状的健康女性的右咬肌处评估口腔和咀嚼肌功能，并且我们再次证实了ADEMG系统在人类咬肌中高达30%MVC的有用性;（3）第三，比较肌筋膜疼痛患者和无症状对照者在次最大自主收缩水平下咬肌MUAP的构型和放电特性，并评估肌筋膜疼痛是否具有神经肌肉疾病中观察到的异常肌电特性。因此，我未能证明MUAP的任何异常构型特性，经常在神经肌肉疾病的情况下识别;（4）最后，我检查了是否颞下颌关节紊乱病（TMD）慢性肌痛患者在头部和颈部区域以外的远程部位疼痛敏感性增加，并评估内源性疼痛抑制系统是否触发缺血性疼痛功能在这些患者中有利。因此，我猜测TMD患者在远端部位的疼痛敏感性增加，我还提供了额外的证据表明，在慢性咀嚼肌痛的TMD患者中，内源性阿片系统可能受损。少

To compare the configurational and firing properties of motor until action potentials (MUAPs) in the masseter muscles between myofascial pain patients and asymptomatic controls at submaximal voluntary contraction levels, and to evaluate whether myofascial pain has abnormal electromyographic properties observed in neuromuscular disorders or not, I performed the below-mentioned four experiments: (1) At first, We explored the feasibility of utilizing the turns per second (TS) and amplitude per turn (AT) in conjunction with surface electrodes as a method for assessing masticatory muscle function, and results showed that the AT increased with contraction at all contraction levels, demonstrating a linear relationship, while the TS showed a nonlinear increase characterized by an initial steep rise followed by a plateau, which was simulated with a third polynomial function. We considered that the TS and AT may provide valuable physiological information about the underlying mechanisms of recrui … More tment and the firing of motor units; (2)Second, I tried to demonstrate the feasibility of utilizing electromyographic decomposing systems (ADEMG) as a means to assess oral and masticatory muscle function using concentric needle electrodes at the right masseter muscles of asymptomatic healthy females, and we reconfirmed the usefulness of the ADEMG systems up to 30% MVC in the human masseter muscles; (3)Third, I compared the configurational and firing properties of MUAPs in the masseter muscles between myofascial pain patients and asymptomatic controls at submaximal voluntary contraction levels, and I evaluated whether myofascial pain has abnormal electromyographic properties observed in neuromuscular disorders or not. Consequently, I failed to demonstrate any abnormal configurational properties of MUAPs, frequently recognized in case of neuromuscular disorders; (4)Finally, I examined whether or not Temporomandibular Disorders (TMD) patients with chronic myalgia have increased pain sensitivity at remote sites outside of the head and neck region, and to evaluate whether endogenous pain inhibitory systems triggered ischemic pain functions favorably in those patients. As a result, I guessed that TMD patients have increased pain sensitivity at remote sites, and I also provided additional evidence that the endogenous opioid systems may become impaired in TMD patients with chronic masticatory myalgia. Less