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Search for Stress Compounds in Crude Drugs

Search for Stress Compounds in Crude Drugs
寻找生药中的应力化合物
批准号:
10671977
负责人:
TAKASUGI Mitsuo
金额:
$2.05万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
1998
资助国家:
日本
项目状态:
已结题
起止时间:
1998 至 1999

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项目成果

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中文摘要
翻译
Stress compounds induced in plant tissues of medicinal plants during the processing of raw materialwere shown as potential constituents of crude drugs. Since stress compounds show biologicalactivities,evaluation of the compounds in crude drugs is very important . Bioassay-directed fractionation of来自药物或相关plants的压力tissues of the stressed tissues of medicinal or相关plants resulted in the isolation ofstress compounds required for authentic analysis .Umbelliferae:Glehnia littoralis, Saposhinikovia divaricata, Angelica acutiloba,and A. acutiloba var. sugiyamae gave psoralen and相关的furanocoumarins;Cnidium officinale gave senkyunolide B. Araceae:Amorphophalus konjac gave two pyrrolidine alkaloids;Colocasia esculenta gave 1 pyrrolidine alkaloid and 3 piperidine alkaloids;Pinellia ternata gave 1 piperidine alkaloid. Paeonia lactiflora gave hederagenin. Acanthopanaxdivaricatum gave scoparone and 2c divaricatum gave D2butenolides. Rheum palmatum gave 3 anthraquinones and 1bianthrone as stress compounds。
英文摘要
Stress compounds induced in plant tissues of medicinal plants during the processing of raw material were shown as potential constituents of crude drugs. Since stress compounds show biological activities, evaluation of the compounds in crude drugs is very important . Bioassay-directed fractionation of plant extracts from the stressed tissues of medicinal or related plants resulted in the isolation of stress compounds required for authentic markers of crude drug analysis .Umbelliferae: Glehnia littoralis, Saposhinikovia divaricata, Angelica acutiloba, and A. acutiloba var. sugiyamae gave psoralen and related furanocoumarins; Cnidium officinale gave senkyunolide B. Araceae: Amorphophalus konjac gave two pyrrolidine alkaloids; Colocasia esculenta gave 1 pyrrolidine alkaloid and 3 piperidine alkaloids; Pinellia ternata gave 1 piperidine alkaloid. Paeonia lactiflora gave hederagenin. Acanthopanax divaricatum gave scoparone and 2 CィイD217ィエD2butenolides. Rheum palmatum gave 3 anthraquinones and 1 bianthrone as stress compounds.
期刊论文(14)
专著(0)
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会议论文
増田隆広: "ハマボウフウ若芽の保存とストレス化合物の産生"食品衛生学雑誌. 40・3. 241-245 (1999)
Takahiro Masuda:“C. japonica 幼芽的保存和应激化合物的生产”《食品卫生杂志》40・3(1999 年)。
DOI: --
发表时间:
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作者: []
通讯作者:
Emi Okuyama: "Anagesic Components of Glehnia Root"Natural Medicines. 52. 491-501 (1998)
Emi Okuyama:“北沙参的止痛成分”天然药物。
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通讯作者:
増田隆広: "ハマボウフウ若芽の保存とストレス化合物の産生"食品衛生学雑誌. 40. 241-245 (1999)
Takahiro Masuda:“Hamaboufu 幼芽的保存和应激化合物的生产”《食品卫生杂志》40. 241-245 (1999)。
DOI: --
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作者: []
通讯作者:
姉帯正樹: "生薬の調製法とストレス化合物" 薬用植物研究. 1998・2. 34-41 (1998)
Masaki Anebi:“生药和胁迫化合物的制备”药用植物研究1998・2。
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共 14 条
    Search for Leads of Drugs from Stress Compounds Induced in Plants
    • 批准号:
      07558209
    • 项目类别:
      Grant-in-Aid for Scientific Research (A)
    • 资助金额:
      $1.22万
    • 财政年份:
      1995
    • 负责人:
      TAKASUGI Mitsuo
    • 依托单位:
    Bioorganic Chemical Studies on Novel Sulfur-Containing Phytoalexins Produced by Crucifers
    • 批准号:
      63470019
    • 项目类别:
      Grant-in-Aid for General Scientific Research (B)
    • 资助金额:
      $4.99万
    • 财政年份:
      1988
    • 负责人:
      TAKASUGI Mitsuo
    • 依托单位:
    海外基金