Analysis of newborn airway aspirate and colostrum collected by midwives : Judging the mother-child health status and influences on nursing care.

1胎龄较短的新生儿NAA、SP-A水平及SP-A水平与总蛋白的比值(TP比值)均呈下降趋势，以呼吸窘迫综合征(RDS)组尤为明显。NAA中含有与呼吸道生理功能有关的类胰蛋白酶(HAT)，我们对NAA中所含的类胰酶进行了生化分析。2.测定了30例正常新生儿呼吸道抽吸物(NAA)中气管、支气管和肺泡成分的含量，并以健康成人的支气管肺泡灌洗液(BALF)和支气管灌洗液(BLF)为对照。NAA可能有助于诊断新生儿呼吸道的病理状态，并比较新生儿和成人之间的生物防御机制。3探讨NAA与孕期和围产期母体因素以及新生儿因素的关系。4 NAA是诊断新生儿呼吸系统疾病的有用样本，对19例无呼吸问题足月新生儿(I组)、14例早产儿(II组)和3例呼吸窘迫综合征(RDS，III组)新生儿NAA中肺表面活性物质(PS)的含量进行了比较。

1 The NAA SP-A level and the ratio of the SP-A level to the total protein level in NAA (the TP ratio) both tended to be lower among neonates born after shorter gestational ages, and they were particularly low among neonates with respiratory distress syndrome (RDS). NAA contains human airway trypsin-like protease (HAT), which is thought to be involved in the physiological functions of the airway, we biochemically analyzed trypin-like enzymes contained in NAA.2 We measured contents of tracheobronchial and alveolar components contained in the newborn airway aspirates (NAA) obtained from 30 normal newborns, with bronchoalveolar lavage fluid (BALF) and bronchial lavage fluid (BLF) from healthy adults as controls. NAA may be useful for diagnosing pathologic conditions in the airway of the newborns, and for comparing the biological defense mechanism between newborns and adults.3 To examined NAA's relationship to maternal factors during pregnancy and in the peri-labor period, and neonatal factors. None of the neonatal factors ana differed significantly between the two groups.4 NAA are useful samples for clinical diagnosis of newborn respiratory disorders, the pulmonary surfactant (PS) content in NAAs from 19 term infants without respiratory problems (Group I) was compared with those from 14 preterm infants (Group II) and 3 infants with respiratory distress syndrome (RDS, Group III).