Isometric Tension and Electromyography during Functional Electrical Stimulation of the Rat Hindlimb Muscles.

大鼠后肢肌肉功能性电刺激期间的等长张力和肌电图。

• 批准号: 10838034
• 负责人: OKAJIMA Yasutomo
• 金额: $ 2.18万
• 依托单位: Keio University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 1998
• 资助国家: 日本
• 起止时间: 1998 至 2000
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-10838034/
• 关键词: Functional Electrical Stimulation; Electromyography; Muscle Fiber Conduction Velocity; Skeletal Muscle

Objective : To clarify electrically-induced muscular fatigue, the relationship between muscle tension and the electromyography was investigated in the rat hindlimb muscles.Methods : Male Wistar rats (16-week-old) were included. Under general anesthesia, tibialis anterior (TA) and soleus (SOL) muscles were exposed and their distal tendons were attached to the force transducer to measure the isometric tension. A small electrode array consisting of stimulating needles and recording bars was placed over the muscle belly, and tetanic electrical stimulation was applied for 30 seconds at a frequency of either 20Hz or 40Hz. Peak-to-peak amplitude and peak latency of the M-wave, and the muscle fiber conduction velocity (MFCV) were analyzed. The MFCVs were corrected to the temperature of 26℃.Results : During tetanic electrical stimulation, progressive amplitude depression and latency increase of the M-waves as well as slowing of the MFCVs were found which were always preceded by decline of the isometric tension. The speed of these changes differed significantly between TA and SOL muscles and between 20 and 40 Hz of stimulation frequencies.Conclusion : Monitoring the M-waves, especially their amplitudes, seems valuable for detecting muscle fatigue before actual tension drops. The results may be of value for automatic control of functional electrical stimulation for the paralyzed muscle in the field of rehabilitation medicine.

目的：为了阐明电诱导的肌肉疲劳，肌张力和肌电图之间的关系进行了研究，在大鼠后肢muscles.Methods：雄性Wistar大鼠（16周龄）。在全身麻醉下，暴露胫骨前肌（TA）和比目鱼肌（SOL），将其远端肌腱连接到力传感器上以测量等长张力。将由刺激针和记录棒组成的小电极阵列放置在肌腹上，并以20Hz或40Hz的频率施加强直电刺激30秒。分析M波的峰间振幅、峰潜伏期和肌纤维传导速度（MFCV）。结果：在强直电刺激时，M波的振幅逐渐降低，潜伏期逐渐延长，MFCV减慢，且常伴随着等长张力的下降。这些变化的速度之间TA和SOL肌肉和20和40 Hz之间的刺激frequency.Conclusion显着不同：监测M波，特别是它们的振幅，似乎有价值的检测肌肉疲劳之前，实际的张力下降。研究结果对康复医学领域瘫痪肌肉功能性电刺激的自动控制具有一定的参考价值。