Preparation of one-dimensional pi-electron system based on DNA-mimetics

基于DNA模拟的一维π电子系统的制备

• 批准号: 11223202
• 负责人: SHIMOMURA Masatsugu
• 金额: $ 24.32万
• 依托单位: HOKKAIDO UNIVERSITY
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research on Priority Areas (B)
• 财政年份: 1999
• 资助国家: 日本
• 起止时间: 1999 至 2001
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-11223202/
• 关键词: DNA; DNA-mimetics; pi-electron; one-dimensional molecular assemblies; template polymerization; single molecule; monolayer; ジアセチレ; トポケミカル重合; 光重合; 鋳型; アゾベンゼン; 会合; 分子配向; コヒーレント

DNA and DNA-mimetics are chosen for preparation of one-dimensional pi-electron systems with controlled nanostructure (chromophore arrangement, number of chromophores, chromophore orientation, etc.) because of their specific molecular recognition, controlled base sequence and molecular wight. Two types of Langmuir monolayers complexed with DNA molecules at the air-water interface were prepared for single DNA stretching and template polymerization of the DNA-mimetics, respectively. Single DNA molecule can be stretched on the solid surface when the ionic complex of a double-stranded DNA and a cationic monolayer was transferred slowly from water surface to the hydrophilic solid surface by using conventional Langmuir-Blodgett technique. The surface monolayer of the diacetylene containing nucleobase amphiphiles parepared as DNA-mimetics can form complementary hydrogen bonds with single stranded DNAs at the air-water interface. The single-stranded DNA molecule can act as a template of photopolymerization of the diacetylene groups in the DNA-mimetics. Combination of two methods will provide a new preparation strategy of single molecular devices having one-dimensional pi-electron system.

选择DNA和DNA模拟物来制备具有可控纳米结构(生色团排列、生色团数量、生色团取向等)的一维皮电子体系。由于其独特的分子识别、可控的碱基序列和分子鬼魂。制备了两种在空气-水界面与DNA分子络合的朗缪尔单分子膜，分别用于单DNA拉伸和DNA模拟物的模板聚合。利用传统的Langmuir-Blodgett技术，当双链DNA和阳离子单层的离子络合物从水表面缓慢转移到亲水的固体表面时，单个DNA分子可以在固体表面拉伸。与DNA模拟分子相比，双乙炔核碱基两亲分子的表面单层可以与单链DNA在空气-水界面形成互补的氢键。在DNA模拟中，单链DNA分子可以作为双乙炔基团光聚合的模板。这两种方法的结合将为具有一维皮电子体系的单分子器件的制备提供一种新的策略。

项目成果

J. Matsumoto: "Photopolymerization of the Diacetylene Nucleobase Monolayers Controlled by Triplex Formation"Mol. Cryst. Liq. Cryst.. 371. 33-36 (2001)

J. Matsumoto：“由三链体形成控制的二乙炔核碱单层的光聚合”Mol。

M.Morisue: "Two-Dimensional Nucleobase Self-Organization Supported by Base-Pairing and Stacking at the Air-Water Interface"Mol.Cryst.Lyq.Cryst. 371. 379-382 (2001)

M.Morisue：“空气-水界面碱基配对和堆积支持的二维核碱基自组织”Mol.Cryst.Lyq.Cryst。

M. Shimomura: "DNA-Mimetics: Towards Novel Molecular Devices Having Molecular Information"Synthetic Metals. in press.

M. Shimomura：“DNA 模拟物：走向具有分子信息的新型分子装置”合成金属。

K.Ijiro: "Base-pair Mapping by Chemical Force Microscopy on Nucleobase Self-Assembled Monolayers"Colloids and Surfaces, A. 198-200. 677-682 (2002)

K.Ijiro：“通过化学力显微镜在核碱基自组装单层上进行碱基对映射”胶体和表面，A.198-200。

J.Matsumoto: "Photopolymerization of the Diacetylene Nucleobase Monolayers Controlled by Triplex Formation"Mol.Cryst.Lyq.Cryst. 371. 33-36 (2001)

J.Matsumoto：“由三链体形成控制的二乙炔核碱单层的光聚合”Mol.Cryst.Lyq.Cryst。