Evaluation of the effects of endocrine disruptors in synthetic compounds on several biological organisms.
Evaluation of the effects of endocrine disruptors in synthetic compounds on several biological organisms.
评估合成化合物中内分泌干扰物对几种生物体的影响。
批准号：
11839026
负责人：
KIMURA Junpei
金额：
$1.54万
依托单位：
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
1999
资助国家：
日本
项目状态：
已结题
起止时间：
1999 至 2000
中文摘要
翻译
点击翻译按钮获取中文摘要
英文摘要
The estrogenic activity of thirty seven endocrine disruptors including byproducts from plastic gloves and food wraps, and chemicals related to nonylphenol, medical drugs and phytoestrogens, were measured by in vitro and in vivo tests. There was a good correlation between the results obtained from two in vitro tests which included a recombinant yeast test and a cultured mammary cancer cell test. Eighteen chemicals were subjected to an in vivo rat vaginal smear test. Those of the chemicals subjected, eight showed a positive correlation between results obtained from the present study and the results from Dodds's results (1938). From these correlation, the evaluation methods of plastic compounds, medical drugs and phytoestrogens in food safety and living environment were discussed.
期刊论文(1)
专著(0)
科研奖励(0)
会议论文
J.Kimura et al.: "Immunohistochemical Localization of Inhibin and Steroidogenic Enzymes in the Ovary of Common Tree Shrew and Northern Smooth-tailed Tree Shrew."Anatomia Histologia Embryologia. 29. 267-271 (2000)
J.Kimura 等人：“普通树鼩和北方光滑尾树鼩卵巢中抑制素和类固醇生成酶的免疫组织化学定位。”解剖组织学胚胎学。
J.Kimura 等人：“普通树鼩和北方光滑尾树鼩卵巢中抑制素和类固醇生成酶的免疫组织化学定位。”解剖组织学胚胎学。
DOI：
--
发表时间：
期刊：
影响因子：
--
作者：
[]
通讯作者：
海外基金