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Home Cervical Smear Test

Home Cervical Smear Test
家庭宫颈涂片检查
批准号:
10051354
负责人:
金额:
$6.37万
依托单位:
依托单位国家:
英国
项目类别:
Grant for R&D
财政年份:
2023
资助国家:
英国
项目状态:
已结题
起止时间:
2023 至 --
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中文摘要
翻译
99.7%的子宫颈癌是由HPV引起的。HPV感染后,子宫颈的癌前病变可能需要大约10年的时间才能发展。这意味着如果早期发现癌前突变,那么宫颈癌可能会被预防。1988年,国民保健制度子宫颈普查计划成立,自实施以来,估计每年挽救多达5000人的生命。尽管有良好的记录,但在英国,大约四分之一的女性没有接受筛查。平均每天有两名妇女死亡,每年约850人死亡。根据英国癌症研究中心的数据,这些死亡的更大比例来自非白人少数民族。世界卫生组织(世卫组织)预测,2018年至2030年期间,宫颈癌新病例每年将从57万例增加到70万例,每年死亡人数将从31.1万例增加到40万例。研究概述了妇女在进行子宫颈涂片检查时面临的障碍。这些症状包括尴尬、害怕疼痛和焦虑。导致疼痛的因素包括解剖尺寸小、子宫后倾、阴道痉挛、无产、更年期(阴道萎缩)、女性生殖器切割(FGM)和先前的性侵犯。“我在做子宫颈抹片检查时感到疼痛。我痛得如此厉害的原因是我的窥镜尺寸不对(我用的是一个有好几个孩子的女人的窥镜)。我从未有过孩子。我为这次经历感到羞愧和尴尬。就好像我应该为疼痛和不适负责。“尽管发现了这些障碍,但进行这项测试的方法在过去144年里没有改变;1878年,托马斯·格雷夫斯修改了爱德华·加布里埃尔·库斯科的窥镜,加入了两个弯曲的金属刀片。“我的医生对我的痛苦不屑一顾,经历过性侵犯的我,巴氏涂片检查从来不是不舒服,而是精神创伤。”LBN创新有限公司正在听取妇女的意见,并开发一种新的紧凑型医疗设备来取代窥镜。透过发展新的涂片测试方法,我们会积极鼓励更多市民参与筛检计划,从而拯救生命。
英文摘要
99.7% of cervical cancer is caused by HPV. Pre-malignant changes to the uterine cervix can take approximately 10 years to develop following HPV infection. This means that if the pre-cancerous mutations are caught early, then cervical cancer may be prevented.In 1988, the NHS Cervical Screening Programme was established and is estimated to have saved up to 5,000 lives a year since its inception. Despite its proven track record, approximately 1 in 4 women in the UK fail to be screened. Two women a day die, on average, with approximately 850 deaths a year. The greater percentage of these deaths, according to Cancer Research UK, is from non-white minority ethnic groups. The World Health Organization (WHO) projects an annual increase in new cases of cervical cancer from 570,000 to 700,000 between 2018 and 2030, with annual deaths increasing from 311,000 to 400,000\.Research outlines the barriers women face undergoing a cervical smear test. These include embarrassment, fear of pain and anxiety. Factors that can contribute towards pain are small anatomical size, a retroverted uterus, vaginismus, nulliparous, menopause (vaginal atrophy), female genital mutilation (FGM) and prior sexual assault."I have experienced pain when having a pap smear done. The reason I had such terrible pain was the wrong speculum size (the one that was used was for a woman who had had several children). I've never had children. I was shamed and embarrassed by the experience...It was almost like I was to blame for the pain and discomfort."Despite these barriers being identified, the methodology for performing this test has not changed for the last 144 years; not since 1878, when Thomas Graves revised Edward Gabriel Cusco's speculum to include two curved metal blades."My doctor dismissed my pain and, having been through sexual assault, pap smears were never just uncomfortable, they were mentally traumatic."LBN Innovations Ltd is listening to women and developing a new, compact medical device to replace the speculum. By developing a new smear test methodology, we will actively encourage more participation in screening programmes and so save lives.
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