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Home Cervical Smear Test

Home Cervical Smear Test
家庭宫颈涂片检查
批准号:
10051354
负责人:
金额:
$6.37万
依托单位:
依托单位国家:
英国
项目类别:
Grant for R&D
财政年份:
2023
资助国家:
英国
项目状态:
已结题
起止时间:
2023 至 --
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中文摘要
翻译
99.7%的宫颈癌是由HPV引起的。在HPV感染后,宫颈癌前病变可能需要大约10年的时间才能发展。这意味着,如果癌症前期的突变被及早发现,宫颈癌就可能被预防。1988年,英国国民健康保险制度的子宫颈筛查计划成立,据估计,自该计划开始以来,每年挽救了多达5000人的生命。尽管有良好的业绩记录,但在英国,大约四分之一的女性没有通过筛查。平均每天有两名妇女死亡,每年大约有850人死亡。根据英国癌症研究中心的数据,这些死亡中更大比例的人来自非白人少数民族。世界卫生组织(WHO)预计,2018年至2030年间,宫颈癌新病例每年将从57万例增加到70万例,每年的死亡人数将从31.1万人增加到40万人。研究概述了妇女接受宫颈涂片检查所面临的障碍。这些症状包括尴尬、对痛苦的恐惧和焦虑。可能导致疼痛的因素包括解剖尺寸小、子宫后倾、阴道痉挛、未分娩、更年期(阴道萎缩)、女性生殖器切割(FGM)和既往性侵犯。我感到如此痛苦的原因是镜片的尺寸不对(使用的是一位生了好几个孩子的妇女)。我从来没有生过孩子。我的经历让我感到羞愧和尴尬……就像我应该为疼痛和不适负责一样。“尽管发现了这些障碍,但进行这项测试的方法在过去的144年里一直没有改变;自1878年托马斯·格雷夫斯修改爱德华·加布里埃尔·库斯科的窥镜,将其包括两个弯曲的金属刀片以来,就没有改变过。”我的医生解除了我的痛苦,而且,在经历了性侵犯之后,宫颈涂片从来不只是不舒服,它们还会造成精神创伤。LBN Innovation Ltd正在听取女性的意见,并开发一种新的、紧凑的医疗设备来取代窥镜。通过发展一种新的涂片检测方法,我们将积极鼓励更多人参与筛查计划,从而拯救生命。
英文摘要
99.7% of cervical cancer is caused by HPV. Pre-malignant changes to the uterine cervix can take approximately 10 years to develop following HPV infection. This means that if the pre-cancerous mutations are caught early, then cervical cancer may be prevented.In 1988, the NHS Cervical Screening Programme was established and is estimated to have saved up to 5,000 lives a year since its inception. Despite its proven track record, approximately 1 in 4 women in the UK fail to be screened. Two women a day die, on average, with approximately 850 deaths a year. The greater percentage of these deaths, according to Cancer Research UK, is from non-white minority ethnic groups. The World Health Organization (WHO) projects an annual increase in new cases of cervical cancer from 570,000 to 700,000 between 2018 and 2030, with annual deaths increasing from 311,000 to 400,000\.Research outlines the barriers women face undergoing a cervical smear test. These include embarrassment, fear of pain and anxiety. Factors that can contribute towards pain are small anatomical size, a retroverted uterus, vaginismus, nulliparous, menopause (vaginal atrophy), female genital mutilation (FGM) and prior sexual assault."I have experienced pain when having a pap smear done. The reason I had such terrible pain was the wrong speculum size (the one that was used was for a woman who had had several children). I've never had children. I was shamed and embarrassed by the experience...It was almost like I was to blame for the pain and discomfort."Despite these barriers being identified, the methodology for performing this test has not changed for the last 144 years; not since 1878, when Thomas Graves revised Edward Gabriel Cusco's speculum to include two curved metal blades."My doctor dismissed my pain and, having been through sexual assault, pap smears were never just uncomfortable, they were mentally traumatic."LBN Innovations Ltd is listening to women and developing a new, compact medical device to replace the speculum. By developing a new smear test methodology, we will actively encourage more participation in screening programmes and so save lives.
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