Home Cervical Smear Test

家庭宫颈涂片检查

• 批准号: 10051354
• 金额: $ 6.37万
• 依托单位: LBN INNOVATIONS LTD
• 依托单位国家: 英国
• 项目类别: Grant for R&D
• 财政年份: 2023
• 资助国家: 英国
• 起止时间: 2023 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=10051354
• 关键词: Home; Cervical; Smear; Test

99.7% of cervical cancer is caused by HPV. Pre-malignant changes to the uterine cervix can take approximately 10 years to develop following HPV infection. This means that if the pre-cancerous mutations are caught early, then cervical cancer may be prevented.In 1988, the NHS Cervical Screening Programme was established and is estimated to have saved up to 5,000 lives a year since its inception. Despite its proven track record, approximately 1 in 4 women in the UK fail to be screened. Two women a day die, on average, with approximately 850 deaths a year. The greater percentage of these deaths, according to Cancer Research UK, is from non-white minority ethnic groups. The World Health Organization (WHO) projects an annual increase in new cases of cervical cancer from 570,000 to 700,000 between 2018 and 2030, with annual deaths increasing from 311,000 to 400,000\.Research outlines the barriers women face undergoing a cervical smear test. These include embarrassment, fear of pain and anxiety. Factors that can contribute towards pain are small anatomical size, a retroverted uterus, vaginismus, nulliparous, menopause (vaginal atrophy), female genital mutilation (FGM) and prior sexual assault."I have experienced pain when having a pap smear done. The reason I had such terrible pain was the wrong speculum size (the one that was used was for a woman who had had several children). I've never had children. I was shamed and embarrassed by the experience...It was almost like I was to blame for the pain and discomfort."Despite these barriers being identified, the methodology for performing this test has not changed for the last 144 years; not since 1878, when Thomas Graves revised Edward Gabriel Cusco's speculum to include two curved metal blades."My doctor dismissed my pain and, having been through sexual assault, pap smears were never just uncomfortable, they were mentally traumatic."LBN Innovations Ltd is listening to women and developing a new, compact medical device to replace the speculum. By developing a new smear test methodology, we will actively encourage more participation in screening programmes and so save lives.

99.7%的宫颈癌是由HPV引起的。 HPV 感染后，子宫颈可能需要大约 10 年的时间才能发生癌前变化。这意味着，如果及早发现癌前突变，则可以预防宫颈癌。 1988年，NHS宫颈筛查计划成立，自启动以来估计每年挽救了多达5,000人的生命。尽管记录良好，但英国约有四分之一的女性未能接受筛查。平均每天有两名妇女死亡，每年约有 850 人死亡。根据英国癌症研究中心的数据，这些死亡中较大比例来自非白人少数族裔。世界卫生组织 (WHO) 预计，从 2018 年到 2030 年，每年宫颈癌新发病例将从 57 万例增加到 70 万例，每年死亡人数从 311,000 例增加到 40 万例。研究概述了女性接受宫颈涂片检查时面临的障碍。这些包括尴尬、害怕疼痛和焦虑。导致疼痛的因素包括解剖尺寸小、子宫后倾、阴道痉挛、未产过、更年期（阴道萎缩）、女性生殖器残割（FGM）和以前的性侵犯。“我在进行子宫颈抹片检查时经历过疼痛。我感到如此剧烈疼痛的原因是窥器尺寸错误（使用的窥器尺寸是为一位有几个孩子的妇女使用的）。我从未生过孩子。我感到羞愧和羞愧 这段经历让我感到尴尬……就好像我要为疼痛和不适负责。“尽管已经发现了这些障碍，但执行这项测试的方法在过去 144 年里没有改变； 1878 年，托马斯·格雷夫斯 (Thomas Graves) 修改了爱德华·加布里埃尔·库斯科 (Edward Gabriel Cusco) 的窥器，加入了两个弯曲的金属刀片。“我的医生消除了我的痛苦，而且，在经历过性侵犯后，子宫颈抹片检查不仅不舒服，还会造成精神创伤。”LBN Innovations Ltd 正在倾听女性的声音，并开发一种新型紧凑型医疗设备来取代窥器。通过开发新的涂片检测方法，我们将积极鼓励更多人参与筛查计划，从而挽救生命。