How mammalian males indirectly control transmission of paternal traits.

哺乳动物雄性如何间接控制父系性状的传递。

• 批准号: DE220101449
• 负责人: Dr Nicole McPherson
• 金额: $ 33.33万
• 依托单位: The University of Adelaide
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Early Career Researcher Award
• 财政年份: 2022
• 资助国家: 澳大利亚
• 起止时间: 2022-01-01 至 2024-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DE220101449
• 关键词: How; mammalian; males; indirectly; control

This project aims to address how environmental insults in males prior to conception are able to modify phenotype of subsequent offspring. This project expects to generate fundamental knowledge in a key biological pathway on how non-genetic factors delivered by sperm at conception are able to program the growth of the developing embryo.The knowledge generated from this project will provide understanding and biological options for responding to, and potentially mitigating the impacts of environmental change on the mammalian reproductive system.

该项目旨在解决男性受孕前的环境损害如何改变随后后代的表型。该项目期望在一个关键的生物学途径中产生基础知识，了解精子在受孕时传递的非遗传因素如何能够规划发育中胚胎的生长。该项目产生的知识将为应对并可能减轻环境变化对哺乳动物生殖系统的影响提供理解和生物学选择。