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Improvement of the SRA distribution in RF capacitive heating of the deep seated tumors

改善深部肿瘤射频电容加热中的 SRA 分布

基本信息

批准号：
12670891
负责人：
HIRAKI Yoshiyuki
金额：
$ 1.34万
依托单位：
Kagoshima University
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
2000
资助国家：
日本
起止时间：
2000 至 2001
项目状态：
已结题

来源：
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-12670891/
关键词：
Distribution of the SAR RF capacitive heating Oval electrodes Dharma doll shaped electrodes deep seated heating 温熱療法交互加温腔内加温皮下脂肪過熱防止

项目摘要

RF capacitive hyperthermia has been used for the treatment of various malignan ttumors combined with radiotherapy and chemotherapy. Though a pair of round electrodes of the optimum size have been used by the position and extension of the tumors, round electrodes often hang out of the surfaces of the human body such as arm, thigh, and neck. We contrived some electrodes with oval, triangle and dharma doll in shape to fit a variety of malignant tumors and investigated the peculiarity of heating using agar phantoms. Though hot spot around the edge of electrodes was slightly stronger in oval electrodes than round electrodes, that of dharmal doll shape electrodes was almost equal to that of round electrodes. Capability of deep position by both oval and dharmal doll shape electrodes was superior to that by round electrodes, as well as selectiveness of treatment site. In clinical use of RF capacative hyperthermia, both oval and dharmal doll shape electrodes seemed useful for the treatment of various malignant tumors.

射频电容热疗已与放疗、化疗联合用于治疗多种恶性肿瘤。虽然根据肿瘤的位置和延伸情况已经使用了一对最佳尺寸的圆形电极，但圆形电极经常悬挂在人体表面，例如手臂、大腿和颈部。我们设计了适合多种恶性肿瘤的椭圆形、三角形和达摩娃娃形状的电极，并研究了琼脂模型的加热特性。虽然椭圆形电极的电极边缘热点比圆形电极稍强，但达摩娃娃形电极的热点几乎与圆形电极相同。椭圆形和达摩娃娃形电极的深部定位能力以及治疗部位的选择性均优于圆形电极。在射频电容热疗的临床应用中，椭圆形和达玛娃娃形电极似乎都可用于治疗各种恶性肿瘤。