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A new applicator of RF capacitive heating for head and neck cancer

一种用于头颈癌的新型射频电容加热治疗仪

基本信息

批准号：
07671021
负责人：
HIRAKI Yoshiyuki
金额：
$ 1.15万
依托单位：
Kagoshima University
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
1995
资助国家：
日本
起止时间：
1995 至 1996
项目状态：
已结题

来源：
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-07671021/
关键词：
Head and neck cancer Deep heating RF capacitive heating U-shape applicator Edge effect 頭頸部腫瘍 SAR分布遮蔽板 Overlay Bolus

项目摘要

We devised a new type of applicator (U-shape applicator), with bending the flat electrode of 15 cm in diameter into U-shape. Japan hyperthermia society QA phantoms were heated with the U-shape applicator and with the flat applicator. The temperature in the phantom was measured with the Teflon coated thermocouples and the vertical sectional thermal distributions after heating were taken with a thermography unit. The untoward edge effect was reduced and favorable thermal distribution was obtained with the U-shape applicator. On the thermal profile after heating, the highest temperature zone was shifted to the shallower sides of the phantom with the flat applicator, and was near the core with the U-shape applicator. The change of the thermal distribution may be not only due to the decrease of the edge effects but the changes of the distance between both electrodes. In the clinical application to one of our co-workers who was suffering hypopharyngeal cancer, pain and other complication were reduced and the maximum temperature of the oral floor and at esophageal inlet was nearly 2ﾟC higher with the U-shape applicator than with the flat applicator. The change of the temperatures may be due to the decrease of the edge effects, the shortening of the distance between both electrodes, and improvement of non-uniform distance from electrodes to skin.U-shape applicator can be expected to play an important role in clinical hyperthermic oncology.

我们设计了一种新型施源器（U形施源器），将直径15厘米的扁平电极弯曲成U形。日本热疗学会QA模型分别用U型加热器和平板加热器加热。用聚四氟乙烯涂层热电偶测量体模中的温度，并用热成像装置拍摄加热后的垂直截面热分布。采用U型加热器可以有效地减小边缘效应，获得良好的热分布。在加热后的热曲线上，最高温度区在扁平施用器的情况下移动到体模的较浅侧，在U形施用器的情况下靠近芯。热分布的变化可能不仅是由于边缘效应的减小，而且是由于两个电极之间的距离的变化。在对患有下咽癌的我们的一位同事的临床应用中，疼痛和其他并发症减少，并且使用U形施源器的口底和食管入口处的最高温度比使用扁平施源器高近2摄氏度。温度的变化可能是由于边缘效应的减小、电极间距离的缩短以及电极与皮肤之间距离的不均匀性的改善，U形加热器有望在临床肿瘤热疗中发挥重要作用。