EVAUATION OF CROSS-SECTIONAL AREA OF CORONARY ARTERIES BY CONDUCTANCE CATHETER : TOWORD ITS APPLICATION TO PTCA

通过电导导管评估冠状动脉横截面积：TOWORD 在 PTCA 中的应用

• 批准号: 12680832
• 负责人: ARAKI Junichl
• 金额: $ 2.3万
• 依托单位: OKAYAMA UNIVERSITY
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2000
• 资助国家: 日本
• 起止时间: 2000 至 2001
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-12680832/
• 关键词: CONDUCTANCE CATHETER; CORONARY STENOSIS; INTRAVASCULAR ULTRASOUND; CORONARY ANGIOGRAPHY; PERCUTANEOUS TRANSLUMINAL CORONARY ANGIOGRAPHY

ObjectivesThe purpose of this study was to evaluate the feasibility of the conductance catheter (CC) method in measuring cross-sectional area (CSA) of small vessels like human coronary arteries.MethodsLumen CSA (A) of phantom tubes (2-10 mm in diameter) and excised canine arteries (n = 10, 2.3-4.5 mm in diameter) were measured with 3-F CC (Acc) and intravascular ultrasound (Aus). To investigate the influence of parallel conductance in accuracy of Ace, solution with various resistivities was applied to the surrounding of the arteries (n = 4).ResultsAcc showed an excellent agreement with phantom model CSA. In the excised arteries, Acc and Aus highly correlated (R2 = 0.906) with each other. When the resistivities of the solution surrounding the vessels was changed, Acc-Aus regression lines were similar regardless of different resistivities.ConclusionsThe conductance method is feasible to measure CSA of small vessels like human coronary arteries.

目的探讨电导导管（CC）法测量人冠状动脉等小血管截面积（CSA）的可行性。方法用3-F CC（Acc）和血管内超声（Aus）测量10根直径为2.3- 4.5mm的离体犬动脉和2-10 mm的体模管的管腔CSA（A）。为探讨平行电导对Ace测量准确性的影响，将不同电导率的溶液应用于动脉周围（n = 4）。在切除的动脉中，Acc和Aus彼此高度相关（R2 = 0.906）。当周围的血管溶液的折射率改变时，Acc-Aus回归线是相似的，而不管不同的折射率。

项目成果

J. ARAKI: "ASSESSMENT OF TOTAL CA2+ HANDLING FOR EXCITATION CONTRACTION COUPLING IN BEATING LEFT VENTRICLE"JOURNAL OF MECHANICS IN MEDICINE AND BIOLOGY. 1-2. 123-138 (2001)

J. ARAKI：“左心室搏动中兴奋性收缩耦合的总 CA2 处理评估”医学与生物学力学杂志。

T.Imaoka: "Evaluation of cross-sectional area of small vessels by a miniature conductance catheter : Toward its application to coronary stenosis"Cardiovascular Engineering : An International Journal. (in press). (2002)

T.Imaoka：“通过微型电导导管评估小血管横截面积：针对其在冠状动脉狭窄中的应用”心血管工程：国际期刊。

T. IMAOKA: "EVALUATION OF CROSS-SECTIONAL AREA OF SMALL VESSELS BY A MINIATURE CONDUCTANCE CATHETER : TOWARD ITS APPLICATION TO CORONARY STENOSIS"CARDIOVASCULAR ENGINEERING : AN INTERNATIONAL JOURNAL. (in press). (2002)

T. Imaoka：“通过微型传导导管评估小血管的横截面积：在冠状动脉狭窄中的应用”《心血管工程：国际期刊》。

G. IRIBE: "NEW CALCULATION OF INTERNAL CA2+ RECIRCULATION FRACTION FROM ALTERNANS DECAY OF POSTEXTRASYSTOLIC POTENTIATION"JAPANESE JOURNAL OF PHYSIOLOGY. 51-2. 143-149 (2001)

G. IRIBE：“新计算来自交替性收缩后增强衰减的内部 CA2 再循环分数”，日本生理学杂志。

J.Araki: "Assessment of total Ca^<2+> handling for excitation-contraction coupling in beating left ventricle"Journal of Mechanics in Medicine and Biology. 1・2. 123-138 (2001)

J.Araki：“左心室兴奋-收缩耦合的总Ca^<2+>处理的评估”医学和生物学力学杂志1・2（2001）。