Behavioral genetic study on higher order mental functions by twin method.

双生法对高阶心理功能的行为遗传学研究。

• 批准号: 13309014
• 负责人: ANDO Juko
• 金额: $ 25.13万
• 依托单位: Keio University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (A)
• 财政年份: 2001
• 资助国家: 日本
• 起止时间: 2001 至 2002
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-13309014/
• 关键词: behavioral genetics; twin method; cognitive abilities; personality; parent-offspring relationship; familial transmission; nature and nurture; structural equation modeling; 遺伝; 環境; 双生児; パーソナリティー; 気質; ワーキングメモリ; 作動記憶; 事象関連電位; 個人差

The main results on research implementation / management are as follows.(1) Expansion of a twins registry : Complete-address investigation of the twins of an area was conducted from the basic resident register focusing on mainly Kanagawa and Chiba Prefecture, the address list (registry) was expanded, and 9000 sets of data was obtained. Thereby the base for big twins research which covers the main areas of Tokyo and the adjoining prefecture was improved.(2) Expansion and maintenance of a twin sample : it appealed for the participation to investigation based on the above-mentioned registry, about 500 sets of adolescence twins' new sample was newly obtained, and the number of twins subjects exceeded 800 sets. Moreover, data was collected also from the parents of the twins concerning a rearing and a societal attitude also from the parents who cooperated until now. Thereby, the research on the structure of the heredity about the transfer in a family of a rearing attitude or a societal attit … More ude and environment was attained.(3) Addition of data and collect ion : From the old sample, the new data of event related potential (ERP), working memory, response time, and an individualized intelligence test (WAIS) were obtained. Moreover, from the new sample, the data about the zygosity diagnosis and the various personalities in question paper, eating behavior, etc. came to hand reliable model search of hereditability and the structure of heredity and environment. Model fitting by structural equation modeling was performed for these analyses.(4) Development of a brain-wave analysis program, an improvement of brain-waves measurement environment : development of the special brain-waves analysis program which suited the present measurement situation installed the shield room for exact brain-waves measurement. Although this was because it was obliged to move the place of a laboratory which performs brain-waves measurement for convenience' sake [unexpected], it will contribute to an improvement of experiment conditions as a result. Less

研究实施/管理方面的主要成果如下：(1)双生子登记表的扩展：从以神奈川县和千叶县为重点的基本户口登记簿开始，对某地区的双胞胎进行了完整的地址调查，扩展了通讯录(登记表)，获得了9000组数据。从而完善了覆盖东京及邻县主要地区的大双胞胎研究基础。(2)双生子样本的扩充与维护：在上述登记的基础上，呼吁参与调查，新获得青春期双胞胎样本约500套，双生子受试者数量超过800套。此外，还从双胞胎的父母那里收集了关于养育方式和社会态度的数据，也从合作到现在的父母那里收集了数据。因此，关于教养态度或社会态度的家庭转移的遗传结构的研究…数据的增加和收集：从旧样本中获得事件相关电位(ERP)、工作记忆、反应时和个体化智力测验(WAIS)的新数据。此外，从新的样本中，关于合子诊断的数据以及试卷中的各种个性、饮食行为等，获得了遗传力、遗传结构和环境结构的可靠模型搜索。脑波分析程序的开发，脑波测量环境的改善：开发适合目前测量情况的专用脑波分析程序，为精确的脑波测量安装屏蔽室。虽然这是因为为了方便起见，不得不将进行脑电波测量的实验室转移到其他地方，但这将有助于改善实验条件。较少

项目成果

Ono, Y., et al.: "Dimensions of temperament as vulnerability factors in depression"Molecular Psychiatry. 7. 948-953 (2002)

Ono, Y., et al.：“气质维度作为抑郁症的脆弱性因素”分子精神病学。

Ando, J., Ono, Y., Wright, M.J.: "Genetic structure of spatial and verbal working memory"Behavior Genetics. 31(6). 615-624 (2001)

Ando, J.、Ono, Y.、Wright, M.J.：“空间和言语工作记忆的遗传结构”行为遗传学。

Kamakura, T., Ando, J., Ono, Y.: "Genetic and environmental influences on self esteem in a Japanese Twin Sample."Twin Research. 4(6). 439-442 (2001)

Kamakura, T.、Ando, J.、Ono, Y.：“遗传和环境对日本双胞胎样本中自尊的影响。”双胞胎研究。

Kamakura, T., Ando, J., Ono, Y.: "Genetic and environmental influences on self-esteem in a Japanese Twin Sample."Twin Research. 4(6). 439-442 (2001)

Kamakura, T.、Ando, J.、Ono, Y.：“遗传和环境对日本双胞胎样本中自尊的影响。”双胞胎研究。

Ando, J., Ono, Y., Wright, M.J.: "Genetic structure of spatial and verbal working memory."Behavior Genetics. 31(6). 615-624 (2001)

Ando, J.、Ono, Y.、Wright, M.J.：“空间和言语工作记忆的遗传结构。”行为遗传学。