Mathematical Analysis of Deformation Behavior in Hip Joint Composed of Functionally Graded Material and Optimization of Material Composition by GA

功能梯度材料髋关节变形行为数学分析及遗传算法材料成分优化

• 批准号: 13650071
• 负责人: SUGANO Yoshihiro
• 金额: $ 1.86万
• 依托单位: Iwate University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2001
• 资助国家: 日本
• 起止时间: 2001 至 2002
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-13650071/
• 关键词: Artificial Hip Joint; Acetabular Cup; Functionally Graded Material; Bioactivity; Stress Relaxation; Material Composition Design; Dynamic Problem; Contact Problem; 不均質性; 動的応力; 不均質中空半球; 材料組成最適化; 力学的適合性; 生体適合性; 遺伝的アルゴリズム; 計算力学

Functionally graded materials (FGMs) which have been developed as one of light-weight structural materials of the reusable rocket engine and flight body in space-plane, could be also applied to create artificial materials with new properties and functions in the medical field. In this study, a material design is performed for the artificial acetabular cup composed of functionally graded material having the bioactivity able to bond to living bone and the function of stress relaxation. The artificial acetabular cup is assumed to be a non-homogeneous hollow hemisphere with arbitrary non-homogeneous mechanical properties only in the radial direction, and then the static and dynamic stresses and displacements in the hemisphere subjected to axisymmetric static and impulsive loadings on the inner spherical surface, are analyzed mathematically, and numerically by using finite element method. The following three analysis models are used : (a) UHMWPE cup fixated to bone with PMMA bone cement ; ( … More b) UHMWPE cup fixated to bone with interface bioactive bone cement ; and c UHMWPE cup with porous AW-glass coating fixated by bone ingrowth into the pores of the coating layer. Furthermore, the contact stress in the functionally graded material artificial hip joint is analyzed. The wear of UHMWPE is a major obstacle limiting the longevity of implanted artificial hip joint. It is now well known that the wear debris of UHMWPE acetabular cup initiates a cascade of adverse tissue response leading to osteolysis and loosening of the article hip joint. Extending the longevity of total hip joint replacements by the improvement of wear behavior has been the subject of ongoing research in the orthopaedic community. The major factor of the UHMWPE wear is the cyclic contact stress. So, material design based on FEM elastic stress analysis is presented for the artificial acetabular cup composed of functionally graded material having the bioactivity able to bond to living bone and the relaxation function of stress on the contact surface and its neighborhood of the femoral head and the acetabular cup subjected to dynamic loadings. Less

功能梯度材料作为可重复使用的火箭发动机和空间飞行器的轻质结构材料之一，也可用于在医学领域创造具有新特性和新功能的人工材料。本研究设计了一种人工髋臼假体，该假体由具有与活体骨结合的生物活性和应力松弛功能的功能梯度材料组成。将人工髋臼假体假定为径向具有任意非均匀力学性质的非均匀中空半球，利用有限元方法对其内球面轴对称静、动态应力和位移进行了数学和数值分析。使用以下三种分析模型：(A)用聚甲基丙烯酸甲酯骨水泥固定在骨上的超高相对分子质量聚乙烯杯；(…更多的b)用界面生物活性骨水泥固定在骨上的UHMWPE杯；以及c UHMWPE杯，其多孔的AW玻璃涂层通过骨嵌入到涂层的孔隙中固定。此外，还对功能梯度材料人工髋关节的接触应力进行了分析。超高相对分子质量聚乙烯(UHMWPE)的磨损是限制人工髋关节寿命的主要障碍。现在众所周知，UHMWPE髋臼的磨损碎屑会引发一系列不良组织反应，导致髋关节骨溶解和松动。通过改善磨损行为来延长全髋关节置换术的寿命一直是骨科领域正在进行的研究课题。循环接触应力是影响UHMWPE磨损的主要因素。因此，提出了基于有限元弹性应力分析的人工髋臼假体的材料设计，该假体是由具有生物活性的能够与活体骨结合的功能梯度材料和在动态载荷作用下股骨头与髋臼接触面上及其邻近区域的应力松弛函数组成的。较少

项目成果

菅野良弘, 西村文仁, 松崎広嘉, 名須川さちえ, 阿波弘治: "生体活性性のある傾斜機能材料製人工股関節の材料設計と動的応力/変形解析"傾斜機能材料論文集. 第15巻1号. 155-160 (2002)

Yoshihiro Kanno、Fumihito Nishimura、Hiroyoshi Matsuzaki、Sachie Nasukawa、Koji Awa：“由生物活性功能梯度材料制成的人工髋关节的材料设计和动态应力/变形分析”功能梯度材料论文集，第 15 卷，第 1 期，155- 160 (2002)

菅野良弘, 西村文仁, 阿波弘治, 那須川さちえ, 森陽彦, 松崎広嘉: "傾斜機能材料からなる人工股関節の動的変形及び応力のFEM解析"日本機械学会東北支部盛岡地方講演会論文集. 011-2. 3-4 (2001)

Yoshihiro Kanno、Fumihito Nishimura、Koji Awa、Sachie Nasukawa、Haruhiko Mori、Hiroyoshi Matsuzaki：“由功能梯度材料制成的人工髋关节的动态变形和应力的有限元分析”日本机械工程师学会东北分会盛冈地区会议论文集。 011-2。3-4（2001）

菅野良弘, 西村文仁, 鬼原寛幸, 松崎広嘉: "傾斜機能材料製人工骨頭ステムの応力/変位のFEM解析と材料組成設計"日本機械学会東北支部八戸地方講演会論文集. 021-2. 61-62 (2002)

Yoshihiro Kanno、Fumihito Nishimura、Hiroyuki Kihara、Hiroyoshi Matsuzaki：“由功能梯度材料制成的人工股骨头柄的应力/位移的 FEM 分析和材料成分设计”日本机械学会东北分会八户地区会议论文集工程师。021-2。61-62（2002）

Y. SUGANO, F. NISHIMURA, M. MATSUZAKI, S. NASUKAWA, K. AWA: "Material Design and Dynamic Stress / Displacement Analysis of a Bioactive Artificial Hip Joint Composed of Functionally Graded Material"Functionally Graded Materials. Vol.15. 155-160 (2002)

Y. SUGANO、F. NISHIMURA、M. MATSUZAKI、S. NASUKAWA、K. AWA：“由功能梯度材料组成的生物活性人工髋关节的材料设计和动态应力/位移分析”功能梯度材料。