Effect of exposure of dying clay 'sendo' on respiratory system

暴露于垂死粘土“sendo”对呼吸系统的影响

• 批准号: 13670337
• 负责人: HARADA Koichi
• 金额: $ 2.18万
• 依托单位: Kumamoto University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2001
• 资助国家: 日本
• 起止时间: 2001 至 2002
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-13670337/
• 关键词: sendos; free silica; macrophage; neutrophile; rush; pneumoconiosis; BALF; tatami mat; 粉じん; 真菌類

Exposing rats to 'Sendos' dust for 10 month in a dust exposing chamber induced symptoms of various inflammatory changes, giant cell tumor, and atelectasis in rats lungs. Activated macrophages and neutrophile were also appeared in bronchoalveolar lavage fluid (BALF) of rat exposed to sendos. Free silica in the dust was found as 13.4%, which was not too high but enough to be noticed. Rush growing farmers started its planting of the seeds in winter time. They harvest the grown rush in summer time. They dye the harvested rush with mud to keep its freshness. When they take out the dried rush from a drying machine and put and keep them into a bags, they expose themselves to fine dust deprived from surface of treated rushes. The danger of 'sendos' dust to the lung was noted by its particle size and content of free silica. We must advise farmers and workers not to inhale the dust who growing and harvesting rush and manufacturing tatami mats.

在染尘室中将大鼠暴露于Sendos粉尘中10个月，引起大鼠肺部各种炎症变化、巨细胞瘤和肺不张的症状。染森多斯大鼠支气管肺泡灌洗液（BALF）中也出现活化的巨噬细胞和中性粒细胞。粉尘中游离二氧化硅含量为13.4%，虽然不太高，但足以引起注意。农民在冬季开始种植种子。他们在夏季收割已长成的灯心草。他们用泥染收割的灯心草以保持新鲜。当他们从干燥机中取出干燥的灯心草并将其放入袋中时，他们将自己暴露在从处理过的灯心草表面剥离的细小灰尘中。通过其颗粒大小和游离二氧化硅的含量，发现了“sendos”粉尘对肺部的危险。我们必须建议农民和工人不要吸入种植和收获匆忙和制造榻榻米垫的灰尘。

项目成果

KOICHI HARADA et al.: "Effect of free silica contained in dying clay sendos on respiratory system"Proceedingus : The 9th Asian Congress of Agricultural Medicine and Rural Health. 234 (2002)

KOICHI HARADA 等人：“染色粘土仙多中含有的游离二氧化硅对呼吸系统的影响”会议记录：第九届亚洲农业医学和农村健康大会。

Koichi Harada, Motohiko Takeya, Takenobu Nakagawa, Shoko Ohmori, and Atsushi Ueda: "Effect of free silica contained in dying 'sendos' on respiratory system"Proceeding: The 9^<th> Asian Congress of Agricultural Medicine and Rural health Working Together fo

Koichi Harada、Motohiko Takeya、Takenobu Nakakawa、Shoko Ohmori 和 Atsushi Ueda：“垂死的‘sendos’中含有的游离二氧化硅对呼吸系统的影响”会议记录：第 9 届亚洲农业医学和农村卫生大会

Koichi Harada, Shoko Ohmori, Atsushi Ueda: "Effect of long time exposure of dying clay 'sendo' on respiratory system in rat"SANGYO EISEIGAKU ZASSHI. Vol. 44 (extra). 456 (2002)

Koichi Harada、Shoko Ohmori、Atsushi Ueda：“长期暴露于垂死粘土‘sendo’对大鼠呼吸系统的影响”SANGYO EISEIGKU ZASSHI。

Koichi Harada, Shoko Ohmori, and Atsushi Ueda: "Effect of long term exposure of dying clay 'send' on respiratory System in rat - Focus on the effect of free silica on the system -"SANGYO EISEIGAKU ZASSHI. Vol. 45 (extra). 628 (2003)

Koichi Harada、Shoko Ohmori 和 Atsushi Ueda：“长期接触垂死粘土‘发送’对大鼠呼吸系统的影响 - 关注游离二氧化硅对系统的影响 -”SANGYO EISEIGKU ZASSHI。

原田幸一, 大森昭子, 上田厚: "い草染土の長期曝露によるラット肺器への影響-い草染土じん肺に及ぼす遊離ケイ酸の修飾作用-"産業衛生学雑誌. 第45巻(印刷中). (2003)

Koichi Harada、Akiko Omori、Atsushi Ueda：“长期接触灯芯草染色土壤对大鼠肺部的影响 - 游离硅酸对灯芯草染色土壤尘肺病的调节作用”，《工业卫生杂志》45（出版中）。 ）