The Establishment of diagnosis and the forensic pathological study on death in the cold.

寒冷死亡诊断的确立及法医病理学研究.

• 批准号: 13670414
• 负责人: SHIONO Hiroshi
• 金额: $ 2.3万
• 依托单位: Asahikawa Medical College
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2001
• 资助国家: 日本
• 起止时间: 2001 至 2003
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-13670414/
• 关键词: Hypothermia; Oxyhemoglobin; First degree frostbite; Wischnewski's spots; Paradoxical undressing; Differences in color between right and left heart blood; Wischnewski斑; 左右心房血の色調査; アルコール; 薬物

A total of 221 cases of fatal hypothermia (152 necropsy cases and 69 autopsy cases) were evaluated. There were 126 malas and 95 females.1)Blood samples from the right and left ventricles were collected in 128 of the 221 cases (63 of the 152 necropsy cases and 65 of the 69 autopsy cases). Differences in color between blood samples from the two ventricles were observed in 48 (76.2%) of the 63 necropsy cases and 62 (95.4%) of the 65 autopsy cases.2)First degree frostbite (congelation erythematosa) observed in 84 (48.0%) of 175 cases.3)Wischnewski's spots were observed in 34 (49.3%, 16 males and 18 females) of 69 autopsy cases.4)Paradoxical undressing was observed in 33 (20.4%, 33 males and 12 females) of the 221cases.5)The alcohol concentration was detected in 42 of 120 necropsy cases and 38 of 50 autopsy cases, and alcohol in 20 and 19 cases, respectively. Thus, alcohol was detected in 39 (22.9%) of a total of 170cases.6)Drugs/poisons were examined in 21 (4 necropsy cases and 17 autopsy cases) of 221 cases, and drugs were detected in 7cases.7)To examine the expression of heat shock protein (hsp) in each organ on autopsy in 20 deaths from hypothermia. Staining of the liver, Kidneys, lungs and pancreas revealed a high level of Ub expression in the cytoplasm and nuclei.

对221例致死性低温(152例尸检和69例尸检)进行了评估。男126例，女95例。1)在221例中，128例(152例尸检中63例，69例尸检中65例)采集了左、右室血。2)175例尸检中84例(48.0%)观察到一级冻伤(凝固性红斑)。3)69例尸检中有34例(49.3%，男16例，女18例)出现Wischnewski斑。4)221例尸检中33例(20.4%，男33例，女12例)出现反常脱衣现象。5)120例尸检中42例和50例尸检中38例检测到酒精浓度酒精分别为20例和19例。因此，170例中有39例(22.9%)检出酒精。6)221例中有21例(4例尸检和17例尸检)检测了药物/毒物，7例检出了药物。7)检测了20例低温死亡尸检时各器官热休克蛋白(HSP)的表达。肝、肾、肺和胰腺的染色显示Ub在细胞质和细胞核中有高水平的表达。

项目成果

斉藤 修, 清水恵子: "凍死の法医学的診断への新しい試み"旭川医科大学研究フォーラム. 4. 29-33 (2002)

斋藤修、清水惠子：“冻死法医诊断的新尝试”旭川医科大学研究论坛。4. 29-33 (2002)。

斉藤 修, 清水恵子ら: "凍死の診断-凍死で認められる特異所見とその頻度について-"犯罪学雑誌. 68. 56-60 (2002)

Osamu Saito、Keiko Shimizu 等人：“冻死诊断 - 在冻死中观察到的独特发现及其频率”犯罪学杂志 68. 56-60 (2002)。

清水恵子, 塩野 寛: "凍死における左右心房血の色調差"犯罪学雑誌. 62(6). 157-160 (1996)

Keiko Shimizu、Hiroshi Shiono：“冻死时左心房和右心房血液的色调差异”《犯罪学杂志》62(6) (1996)。

塩野 寛, 清水恵子: "外気温氷点下での死体温度降下速度について"犯罪学雑誌. 61(1). 1-5 (1995)

Hiroshi Shiono、Keiko Shimizu：“关于室外冰冻温度下尸体的温度下降速度”《犯罪学杂志》61(1) (1995)。

清水恵子, 塩野 寛: "凍死の法医学的診断へのCO-オキシメーターの応用"日法医誌. 52(3). 196-201 (1998)

Keiko Shimizu、Hiroshi Shiono：“CO 血氧仪在冷冻致死法医诊断中的应用”《日本法医学杂志》52(3)（1998）。