Clinical anatomical study for development of new approaches tothe skull base

开发颅底新方法的临床解剖学研究

• 批准号: 13671770
• 负责人: KISHIMOTO Seiji
• 金额: $ 2.18万
• 依托单位: Tokyo Medical and Dental University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2001
• 资助国家: 日本
• 起止时间: 2001 至 2003
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-13671770/
• 关键词: Skull Base; Surgery; Anatomy; 3D-reconstruction; Vascularity of Tissue; 3次元再構築; 頭蓋低

1.Anatomical study of the skull baseAnatomical study for development of new surgical approaches to the skull base was performed using 10 cadavers.Usually, surgical approach to the inferior aspect of the skull base needs large facial skin incision. It causes postoperative facial scar and deformity and remarkably deteriorates the QOL.On the other hand, when newly developed techniques, for example, Facial Dismasking method or be Fort 1 Osteotomy approach, are applied, the inferior aspect of the skull base can be approached without large facial scar. However there might be a limitation of the extent of the exposure of the surgical field if those approaches are applied. Using cadaver dissections, it was confirmed that extent of surgical field approached by new methods is the same as that approached by conventional method.2. Three-dimensional reconstruction of the skull baseAnatomical 3-D n; construction of the skull base is not completed yet. However, new clinical application of the CT image-guided navigation system was developed for simulation surgery of the skull base.3. Vascularity of the various exposed tissue in the skull base surgery.In order to expose the deep part of the skull and face, a lot of skeletons and soft tissues in the face need to be removed.After extirpation of the lesion, those tissues are restored. For stable reduction, preservation of the vascularity of the tissues is important. Using Laser Doppler method, blood flow of those tissues was examined during the skull base surgery. The result will be analyzed, later on.

1.颅底的解剖学研究为探索颅底手术新入路提供解剖学资料。另一方面，当应用新的技术，如面部暴露法或Fort 1截骨入路时，可以接近颅底的下侧面，而不会产生大的面部瘢痕。然而，如果采用这些入路，可能会限制术野的暴露程度。经尸体解剖证实，新方法与传统方法手术入野范围相同.颅底的三维重建解剖学三维n;颅底的构建尚未完成。然而，CT图像引导导航系统的新的临床应用被开发用于颅底的模拟手术.颅底手术中各种暴露组织的血管。为了暴露颅骨和面部的深部，需要去除面部的大量骨骼和软组织。在切除病变后，这些组织被恢复。为了稳定复位，保留组织的血管是很重要的。应用激光多普勒技术，在颅底手术中检测这些组织的血流。稍后将对结果进行分析。

项目成果

岸本誠司: "上顎洞進行癌と鼻副鼻腔手術"JOHNS. 18. 1649-1654 (2002)

Seiji Kishimoto：“上颌窦和鼻窦手术的晚期癌症”JOHNS。18。1649-1654（2002）

岸本誠司: "小児頭頸部悪性腫瘍の診断と治療"小児外科. 34. 337-1341 (2002)

Seiji Kishimoto：“小儿头颈部恶性肿瘤的诊断和治疗”小儿外科。34。337-1341（2002）。

Y.Kimura, N.Nishimiura, S.Kishimoto: "Lipoma in the deep lobe of the parotoid gland : a case report"Auris Nasus Larynx. 29. 61-65 (2002)

Y.Kimura、N.Nishimiura、S.Kishimoto：“腮腺深叶脂肪瘤：病例报告”Auris Nasus Larynx。

川島慶之, 小林麻里, 飯田秀夫, 大野喜久郎, 石川紀彦, 岸本誠司: "前頭蓋底、眼窩へ進展した篩骨洞原発Cement-ossifying Fibromaの一例"頭頸部外科. 12. 71-75 (2003)

Yoshiyuki Kawashima、Mari Kobayashi、Hideo Iida、Kikuro Ohno、Norihiko Ishikawa、Seiji Kishimoto：“一例源自筛窦并延伸至前颅底和眼眶的水泥骨化纤维瘤”头颈外科 12. 71-。 75 (2003)

S.Watanabe.: "Maxillary swing approach to the naso-and oropharyngeall tumor."Stomato-pahrvngol. 15. 369-377 (2003)

S.Watanabe.：“鼻和口咽肿瘤的上颌摆动方法。”Stomato-pahrvngol。