Investigation of the Inner Ear Fluids by Means of Measurements of Blood Flow, Oxygen Tension and Hydrostatic Pressure

1.本文同时测定了豚鼠内淋巴和外淋巴的氢清除率（HC），并计算HC的T_（1/2）作为内耳液代谢的指标。结果表明：（1）内淋巴HC的T1/2明显短于外淋巴HC的T1/2。2)速尿对内淋巴和外淋巴的T1/2 HC均无明显影响。3)甘油能显著缩短内淋巴和外淋巴HC的T1/2.采用伺服调零压力测量系统同时测量豚鼠内淋巴和外淋巴的流体静压。在生理条件下，内淋巴和外淋巴的静水压力无明显差异。在缺氧期间和甘油给药后，两种压力之间也没有差异。

1. Hydrogen clearance (HC) of the endolymph and perilymph in guinea pigs was simultaneously measured and T1/2 of HC was calculated as an index of the metabolism of the inner ear fluids. The results are as follows: 1)T1/2 of HC of the endolymph was significantly shorter than that of the perilymph. 2) Furosemide induced no significant change of T1/2 HC of neither the endolymph nor the perilymph. 3) Glycerol significantly shortened T1/2 of HC in both of the endolymph and perilymph.2. Hydrostatic pressures of the endolymph and perilymph in guinea pigs were measured simultaneously using servo-nulling pressure measuring system. On physiological condition, there was no difference between the hydrostatic pressures of the endolymph and erilymph. During anoxia and after the administration of glycerol, there was no difference between the two pressures, also.