Examination of application of photocatalyst titanium oxide in dentistry and mouth domain

提出了将二氧化钛光催化剂反应转化为生命体（医疗器械和医药材料）利用的研究。应用于口腔癌医学治疗的灭菌效果，（防脏）和TiO_2颗粒的TiO_2涂层到牙科人工材料。此外，为了将光学辐照应用于TiO_2光催化剂反应的牙科医学治疗和口腔外科领域的医学治疗，还尝试了光学辐照。本研究被认为是对口腔口腔疾病高安全性医学治疗方法的发展。二氧化钛光触媒颗粒在口腔癌医学治疗中的应用探讨。在口腔癌源性培养细胞（SCC， ACC）培养液中联合使用抗肿瘤药物阿达拉美辛。在体外进行紫外线照射后，并检测其对肿瘤细胞的杀伤效果。为了有效地介绍TiO_2光催化剂颗粒在裸鼠体内抗肿瘤作用的检测方法。针对某癌症机构的固体型癌症（SCC和ACC），研制了将TiO_2包覆成金色颗粒的遗传枪枪弹。然后用基因枪将金（TiO_2）和抗肿瘤药物包被颗粒驱动到肿瘤组织中，进行光照射并检测其抗肿瘤效果。病理组织观察发现，抗肿瘤药物和光催化剂TiO_2在所有上皮层中部分粘附金颗粒。重点观察大鼠口膜上皮的角化层，由底部结缔组织组成的上皮呈微小的深褐色颗粒。此外，病理组织研究不接受改变。不进行紫外线照射的组在植入抗肿瘤药物和光催化剂TiO_2粘附金后。颗粒观察到泡形成观和上皮缺损（溃疡观）。病理观察后1 - 2天上皮下组织。本实验结果提示，通过UV照射调节药物（如抗肿瘤药物）的组织敏感性的模型效应发挥可以预期TiO_2Now，并对药物（如抗肿瘤药物）在病理改变部位（肿瘤组织）的局部作用进行了检测。它开始于医学治疗判断的实验。它的作用是对药物进行光照射的开关控制。其次，在牙科龋齿医疗时使用的树脂材料中加入TiO_2，考察其对龋齿的防菌效果。此外，还对保护菌对口腔感染（包括牙周病）的作用及其应用进行了实验研究。少

Research which turns a TiO_2 photocatalyst reaction to the utilization of a life object (medical apparatus and medicine material) is advanced. The application of oral cancer medical treatment by the sterilization effect, (guard dirty) and TiO_2 particle by coating of TiO_2 to the artificial material for dentistries. Additionally optical irradiation was tried for the purpose of application to the dentistry medical treatment of a TiO_2 photocatalyst reaction, and the medical treatment of an oral surgery domain. This research is considered the development of high medical treatment methods of safety to disease of dentistry mouth domain.Examination of the application to oral cancer medical treatment of TiO_2 photocatalyst particle TiO_2 particle. The antineoplastic drugs (adraremaishin) were used together in the culture solution of oral cancer origin established cultivation cell (SCC, ACC). UV irradiation after addition was performed, and the level of in vitro examined againtist cancer cell … More effect. In order to introduce efficiently the examination of TiO_2 photocatalyst particle about the anti-neoplasm effect in a nude-mouse (Balb/c). A solid type cancer (SCC and ACC) in a cancer organization, the cartridge of the heredity gun in which TiO_2 was coated to a golden particle was manufactured. Furthermore, after driving the coated particle with gold (TiO_2) and the antineoplastic drug in a neoplasm organization using a gene gun, optical irradiation was performed and examination of the anti-neoplasm effect was performed.With the pathology organization study-view, the antineoplastic drug and the photocatalyst TiO_2 adhesion golden particle were observed in part with all epithelium layers. Focusing on the cornification layer of rats mouth membrane epithelium by the bottom connective tissue of an epithelium as a minute particle of dark brown. Moreover, change was not accepted in the pathology organizational study. The group which did not carry out UV irradiation after inserting an antineoplastic drug and a photocatalyst TiO_2 adhesion golden. Particle observed the bubble formation view ad the epithelium deficit (ulcer view). Uunder the epithelium one-two days after pathology organizational study. It was suggested from this result that the model-effect exertion which adjusts the organizations susceptibility of medicines, such as an antineoplastic drug, by UV irradiation On-Off can expect TiO_2Now, examination about the local effect of medicines, such as an antineoplastic drug in a pathological change part (neoplasm organization), was performed. It started about the experiment of the judgment of the medical treatment. It effect by carrying out On-Off control a medicine from optical irradiation's.Second, TiO_2 was added to the resin material used at the time of dentistry dental caries medical treatment, and guard bacterium effect over dental caries was examined. Furthermore, the experimental examination towards guard bacterium effect over mouth infection including a periodontium disease and its utilization is continued. Less