A Study on Recovery of Dynamic Balance from Intravenous Sedation for Dental Treatment in the Elderly

老年牙科静脉镇静恢复动态平衡的研究

• 批准号: 13672073
• 负责人: FUJISAWA Toshiaki
• 金额: $ 2.3万
• 依托单位: HOKKAIDO UNIVERSITY
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2001
• 资助国家: 日本
• 起止时间: 2001 至 2002
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-13672073/
• 关键词: DYNAMIC BALANCE; INTRAVENOUS SEDATION; THE ELDERLY; MIDAZOLAM; RECOVERY; PRICISE BALANCE TEST; SIMPLE BALANCE TEST

The recovery of dynamic balance accompanied by movement of the center of gravity from intravenous sedation with midazolam in elderly male volunteers was compared with that of young male volunteers. The dynamic balance was evaluated using computerized dynamic posturography (CDP) after obtaining similar sedation levels (with eyes closed and immediate responses to verbal commands), and was also compared with conventional static balance. Moreover, we investigated the correlations of various simple clinical balance tests with precise dynamic posturography. The conclusions were as follows.1. Postural balance function declined more in older subjects than in young subjects, and the difference between the young and old was greater with dynamic posturography than with static posturography, even before sedation.2. The recovery of dynamic balance function during intentional leaning of the subject's body was more delayed in older subjects than in young subjects after intravenous sedation.3. CDP with unexpected perturbations may be an excellent method that sensitively detects inhibition of balance function by intravenous sedation with midazolam.4. The recovery time for dynamic balance against perturbation stimuli in the elderly was 80 minutes after the injection of midazolam, just like that of young adults when the optimal amount of the sedative was carefully administered.5. The maximum walking speed test and 'timed up and go test' were useful simple dynamic balance tests.

将老年男性志愿者与年轻男性志愿者静脉注射咪达唑仑镇静后动态平衡的恢复情况以及重心移动进行比较。在获得相似的镇静水平（闭眼和对口头命令的立即反应）后，使用计算机动态姿势图（CDP）评估动态平衡，并与传统的静态平衡进行比较。此外，我们调查了各种简单的临床平衡测试与精确的动态姿势图的相关性。主要结论如下：1.老年人的姿势平衡功能比年轻人下降得更多，即使在镇静前，动态姿势图的年轻人和老年人之间的差异也大于静态姿势图.静脉镇静后，老年受试者身体有意倾斜时的动态平衡功能恢复较年轻受试者延迟. CDP与意外扰动可能是一个很好的方法，敏感地检测抑制平衡功能的静脉镇静咪达唑仑。老年人在注射咪达唑仑后80 min恢复对干扰刺激的动态平衡，与年轻人在谨慎使用最佳剂量镇静剂时的恢复时间相似.最大步行速度试验和“计时启动试验”是有用的简单动平衡试验。