Intercenter comparison studies for patients with unilateral cleft lip and palate in Japan

目的：研究对象和方法：1992-1994年，在6个唇腭裂中心（新泻大学、东北大学、东京大学、昭和大学、爱知学院大学和大坂大学）治疗的95例单侧唇腭裂患者。结果：6个中心的治疗方案完全不同，各中心均采用各自的治疗方法。此外，我们还发现了一些关于操作系统和案例的趋势，分析可以从多个方面考察各种影响因素。然而，当我们在收集文献时考虑偏倚时，似乎有必要对正颌治疗的存在、唇成形术、腭成形术的时间、开始正畸治疗的时间、病例数的不均匀性进行相关性解释。

Objective : The aim of this study is to establish the effective and treatment of unilateral cleft lip and palate.Subjects and Methods : 95 unilateral cleft lip and palate cases bone in 1992-1994, and treated at 6 cleft lip and palate centers (Niigata University, Tohoku University, Tokyo University, Showa University, Aichi-Gakuin University and Osaka University.) We examined 5 factors (1.protocol,2.lateral cephalograms, 3.Study models.4.Lip and Nose form,5.Speech therapy)Results : Six centers were different about treatment protocol entirely, and each centers treated it with an original treatment system. In addition, we found some tendency about operation system and cases, and analysis was able to examine various influence factors from many aspects. However, when we considered bias at the time of document collection, it seemed that it was necessary to perform interpretation about relevance with presence of orthognatic treatment, time of chiloplasty, palatoplasty, and timing of starting orthodontic treatment, unevenness off the number of the cases.