Microscopic Structure of Aqueous Solutions Involving Amino Acid Molecules with Different Optical Activities

不同旋光性氨基酸分子水溶液的微观结构

• 批准号: 14540509
• 负责人: KAMEDA Yasuo
• 金额: $ 1.86万
• 依托单位: Yamagata University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2002
• 资助国家: 日本
• 起止时间: 2002 至 2003
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-14540509/
• 关键词: neutron diffraction; isotopic substitution method; alanine molecule; optical activity; intermolecular hydrogen bonds; solution structure; glycine molecule; urea molecule; 中性子回析; 水和構造

In order to investigate microscopic properties on the structure of aqueous solutions that involve amino acid molecules with different optical activities, following structural analyses have been carried out in this project;1)Hydrogen-bonded structure in aqueous 2.5 mol% D, L-and L-alanine heavy water solutions by means of the TOF and reactor neutron diffraction measurements.2)Determination of partial structure functions (aHH(Q), aXH(Q) and aXX(Q), X: O, C and N) of aqueous 2.5 mol% D, L-and L-alanine solutions studied by neutron diffraction with the H/D isotopic substitution method.3)Hydration structure around the amino group of the urea molecule studied by neutron diffraction with ^<14>N/^<15>N and H/D isotopic substitution methods.4)Hydration structure around the methyl group of the alanine molecule in aqueous solutions studied by neutron diffraction with the H/D isotopic substitution method.5)Hydration structure around the carboxyl group of the acetate ion studied by ^<12>C/^<13>C isotopic substitution method.

为了研究具有不同光学活性的氨基酸分子水溶液结构的微观性质，本项目进行了以下结构分析：1）通过TOF和反应堆中子衍射测量在2.5mol%D、L-和L-丙氨酸重水水溶液中的氢键结构。2）部分结构函数（aHH（Q），aXH（Q）和aXX（Q），X：O，C和N）。3）用~ N/~ N和~ H/D同位素取代法研究尿素分子氨基周围的水合结构。4）用中子衍射法研究尿素分子氨基周围的水合结构<14><15>。用中子衍射H/D同位素取代法研究了丙氨酸分子甲基周围的水化结构。5）用^ C/^ C同位素取代法研究了乙酸根离子羧基周围的水化结构<12><13>。

项目成果

Y.Kameda et al.: "Structure of Concentrated Aqueous Lithium Alaninate Solutions"KENS REPOER. (in press). (2004)

Y.Kameda 等人：“浓缩丙氨酸锂水溶液的结构”KENS REPOER。

Y.Kameda et al.: "Hydration Structure around the Carboxyl Group Studied by Neutron Diffraction with ^<12>C/^<13>C and H/D Isotopic Substitution Methods"Journal of Solution Chemistry. in press. (2004)

Y.Kameda等人：“通过中子衍射用^ 12 C/^ 13 C和H/D同位素取代方法研究羧基周围的水合结构”溶液化学杂志。

Y.Kameda, M.Yaegashi, M.Imano, H.Naganuma, K.Mochiduki, T.Usuki, O.Uemura: "Hydrogen-Bonded Structure in Concentrated Aqueous DL-and L-Alanine Solutions"JAERI-Review(日本原子力研究所). 2002・14. 193-194 (2002)

Y.Kameda、M.Yeegashi、M.Imano、H.Naganuma、K.Mochiduki、T.Usuki、O.Uemura：“浓缩 DL 和 L-丙氨酸水溶液中的氢键结构”JAERI 审查研究所）。 2002・14。193-194（2002）

Y.Kameda et al.: "Inelasticity Effect on Neutron Scattering Intensities of the Null-H_2O"Journal of Neutron Research. (in press). (2004)

Y.Kameda 等人：“Inelasticity Effect on Neutron Scattering Intensities of the Null-H_2O”Journal of Neutron Research。

Y.Kameda, et al.: "Inelasticity Effect on Neutron Scattering intensities of the Null-H_2O"Journal of Neutron Research. (in press). (2004)

Y.Kameda 等人：“Inelasticity Effect on Neutron Scattering Intensities of the Null-H_2O”Journal of Neutron Research。