Development of intelligent computer aided diagnosis system of medical images based on navigation of virtual human body

基于虚拟人体导航的医学图像智能计算机辅助诊断系统的开发

• 批准号: 15300180
• 负责人: MORI Kensakuk
• 金额: $ 10.5万
• 依托单位: Nagoya University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B)
• 财政年份: 2003
• 资助国家: 日本
• 起止时间: 2003 至 2005
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-15300180/
• 关键词: navigation diagnosis; segmentation; anatomical knowledge database; computer aided diagnosis; real-time navigation; user interface; CT image; virtual human body; CT画像; 仮想化内視鏡; 可視化; コンピュータ支援画像診断; 臓器アトラス

Purpose of this research was to develop an intelligent navigation based diagnosis system of medical images based on navigation of virtual human body. We discussed a completely novel system which enables a medical doctor to diagnose medical images efficiently by automatically detecting the locations and status of abnormal regions and by superimposing them on internal views of virtualized human body.(1) Development of real-time navigation method based on high dimensional medical imagesInput image of this system is three or four dimensional image which includes precise human body information. We investigated fast navigation methods inside virtualized human body(2) Construction of anatomical knowledge databaseStorage methods of anatomical knowledge of chest and abdominal organs were discussed. Here, we investigated representing methods of anatomical knowledge on computer. As examples of anatomical knowledge database, bronchus name database and organ atlases were constructed.(3) Development … More of recognition methods of organsUsing anatomical knowledge database constructed above, we developed a method for recognizing multi organs simultaneously.(4) Development of methods for recognizing and understanding high dimensional medical imagesUsing the anatomical knowledge database, algorithms for detecting, classifying and comparing abnormal regions were examined. As an example of integration of multi modal images, image processing methods for PET-CT images were investigated.(5) Development of real-time displaying algorithm of assistance information of diagnosisWe discussed algorithms for displaying assistance information such as results of abnormal region detection and anatomical structure recognition in real time. Here, assistance information includes not only marking results of abnormal regions but also anatomical names concerning with the regions.(6) Practical evaluation of the system in the clinical fieldWe created a prototype system of navigation diagnosis by integrating the methods we have developed. The system was evaluated by clinicians. Less

本研究的目的是在虚拟人体导航的基础上，开发一个基于智能导航的医学图像诊断系统。我们讨论了一个全新的系统，使医生能够诊断医学图像有效地通过自动检测异常区域的位置和状态，并将它们叠加在虚拟人体的内部视图。(1)基于高维医学图像的实时导航方法的研究本系统的输入图像是包含精确人体信息的三维或四维图像。（2）解剖知识库的构建探讨了胸腹部器官解剖知识的存储方法。本文研究了解剖学知识在计算机上的表示方法。作为解剖知识库的实例，建立了支气管名称数据库和器官图谱。(3)发展 ...更多信息 利用上述建立的解剖知识库，提出了一种多器官同时识别的方法。(4)高维医学图像识别与理解方法的研究利用解剖学知识库，研究了异常区域的检测、分类和比较算法。作为多模态图像融合的一个实例，研究了PET-CT图像的处理方法。(5)诊断辅助信息实时显示算法的研究讨论了异常区域检测结果、解剖结构识别结果等辅助信息的真实的实时显示算法。这里，辅助信息不仅包括异常区域的标记结果，还包括与该区域有关的解剖学名称。(6)该系统在临床领域的实际评估我们通过整合我们开发的方法创建了一个原型系统的导航诊断。临床医生对该系统进行了评价。少

项目成果

CADシステムとしての仮想化内視鏡システムとそのがん検診・診断への応用

虚拟内窥镜系统作为CAD系统及其在癌症筛查和诊断中的应用

• 发表时间: 2005
• 期刊: 日本がん検診・診断学会誌 第12巻,第2号
• 作者: Takao Someya;Takayasu Sakurai;片山新也;Shojun Hino;森 健策
• 通讯作者: 森 健策

CAD systems based on visualization and deformation of virtualized human body

基于虚拟人体可视化变形的CAD系统

• 发表时间: 2006
• 期刊: Medical Image Technology 24, 2
• 作者: 森 健策;Kensaku Mori
• 通讯作者: Kensaku Mori

肺気腫領域抽出のための肺野内CT値補正法の改善

肺气肿区域提取肺野CT值校正方法的改进

• 发表时间: 2005
• 期刊: 平成17年度電気関係学会東海支部連合大会講演論文集
• 作者: 森 健策;Kensaku Mori;Jiro Nagao;Yoshio Watanabe;北坂 孝幸;Torsten Rohlfing;宮本 秀昭;林 雄一郎;Daniel B.Russakoff;森 健策;森 健策;Yoshio Watanabe;Takayuki Kitasaka;Torsten Rohlfing;Hideaki Miyamoto;Yuichiro Hayashi;Daniel B.Russakoff;Kensaku Mori;Masaki Mori;Hiroshi Natori;Daisuke Deguchi;Kensaku Mori;Takayuki Kitasaka;長尾 慈郎;石原 考二;高畠 博嗣;林 雄一郎;小田 昌宏;伊藤 大樹;石原 考二;佐藤 嘉晃;伊藤 大樹;石原 考二
• 通讯作者: 石原 考二

Development of a Method for Specifying Three Dimensional Interested Regions on Volume Rendered Images and Its Application to Virtual Endoscope System

体绘制图像三维感兴趣区域指定方法的开发及其在虚拟内窥镜系统中的应用

• 发表时间: 2004
• 期刊: IEICE Trans. On Information and Systems J87-D-II, 1
• 作者: 森 健策;Kensaku Mori;Jiro Nagao;Yoshio Watanabe;北坂 孝幸;Torsten Rohlfing;宮本 秀昭;林 雄一郎;Daniel B.Russakoff;森 健策;森 健策;Yoshio Watanabe;Takayuki Kitasaka;Torsten Rohlfing;Hideaki Miyamoto;Yuichiro Hayashi;Daniel B.Russakoff;Kensaku Mori;Masaki Mori;Hiroshi Natori;Daisuke Deguchi;Kensaku Mori;Takayuki Kitasaka;長尾 慈郎;石原 考二;高畠 博嗣;林 雄一郎;小田 昌宏;伊藤 大樹;石原 考二;佐藤 嘉晃;伊藤 大樹;石原 考二;渡辺 恵人;早瀬 陽介;岡 宏樹;林 雄一郎;林 雄一郎;森 健策;森 健策;Shigeto Watanabe;Yosuke Hayase;Hiroki Oka;Yuichiro Hayashi
• 通讯作者: Yuichiro Hayashi

Fast and Accurate Bronchoscope Tracking using Image Registration and Motion Prediction

使用图像配准和运动预测快速准确地进行支气管镜跟踪

• 发表时间: 2004
• 期刊: Lecture Notes in Computer Science 3217-2
• 作者: 森 健策;Kensaku Mori;Jiro Nagao;Yoshio Watanabe;北坂 孝幸;Torsten Rohlfing;宮本 秀昭;林 雄一郎;Daniel B.Russakoff;森 健策;森 健策;Yoshio Watanabe;Takayuki Kitasaka;Torsten Rohlfing;Hideaki Miyamoto;Yuichiro Hayashi;Daniel B.Russakoff;Kensaku Mori;Masaki Mori;Hiroshi Natori;Daisuke Deguchi;Kensaku Mori;Takayuki Kitasaka;長尾 慈郎;石原 考二;高畠 博嗣;林 雄一郎;小田 昌宏;伊藤 大樹;石原 考二;佐藤 嘉晃;伊藤 大樹;石原 考二;渡辺 恵人;早瀬 陽介;岡 宏樹;林 雄一郎;林 雄一郎;森 健策;森 健策;Shigeto Watanabe;Yosuke Hayase;Hiroki Oka;Yuichiro Hayashi;Kensaku Mori;Kensaku Mori;Junichiro Toriwaki;林 雄一郎;江間 慎弥;出口 大輔;Jiro Nagao
• 通讯作者: Jiro Nagao