The effect of the muscular training on joint laxity and muscle extensibility

肌肉训练对关节松弛度和肌肉伸展性的影响

• 批准号: 15300224
• 负责人: NAKAJIMA Hiroyuki
• 金额: $ 6.27万
• 依托单位: Nippon Sport Science University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B)
• 财政年份: 2003
• 资助国家: 日本
• 起止时间: 2003 至 2005
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-15300224/
• 关键词: joint laxity; muscle extensibility; animal model; eccentric contraction; connectin; 動物モデル; 伸張性トレーニング; 筋複合体; 性差; 動物実験モデル; 非接触型靭帯損傷; エキセントリック収縮; 下腿三等筋

In general, the appropriate joint stiffness has been regarded to prevent injuries and improve physical activities. In this study, we aimed to elucidate the effects of the muscular training on joint laxity and muscle extensibility. At first, we developed the animal models to evaluate joint laxity. Then, we examined the effect of acute and chronic exercise. The obtained results are summarized as follows ;1.We firstly developed the device to evaluate the flexibility of rat ankle joint. This house-made2.By using our developed device, we found that adult rat ankle joint showed lower laxity in comparison to young rat as reported in human studies.3.We also found the gender differences in rat ankle joint laxity as reported in human studies. The gastrocnemius muscle extensibility and connectin isoform compositions also differed.4.A bout of lengthening contractions on rat gastrocnemius muscle tentatively decreased rat ankle joint flexibility and increased rat gastrocnemius extensibility. We also … More confirmed that the passive tension of the exposed gastocnemius was significantly higher than that of the non-treated control. The muscle wet weights were identical in both groups, suggesting that the absence of edema. Interestingly, this phenomenon was only seen in young rats.5.We investigated the effects of repeated eccentric exercise (20 days) for rat gastrocnemius muscle on ankle joint stiffness and titin (connectin) isoform composition. After the prolonged eccentric exercise, the wet weight of medial gastrocnemius muscle significantly increased. Myosin-ATPase staining showed a decrease in the percentage of type IIB fibers and an increase in the percentage of type IIA fibers. We found that the ankle joint stiffness was significantly smaller in eccentric-exercise group than in sham-operated isometoric trained group. Above all, we conclude that chronic eccentric exercise increase both muscular strength and joint laxity.We are now considering that the prolonged eccentric exercise posses peculiar and should be useful for conditioning and prevention for sport-related injuries. Less

一般来说，适当的关节刚度被认为可以防止受伤并改善身体活动。在这项研究中，我们旨在阐明肌肉训练对关节松弛和肌肉伸展性的影响。首先，我们开发了动物模型来评估关节松弛度。然后，我们检查了急性和慢性运动的效果。所得结果总结如下： 1.首次研制了大鼠踝关节灵活性评价装置。这个自制的2.通过使用我们开发的设备，我们发现与人类研究中报告的年轻大鼠相比，成年大鼠踝关节表现出较低的松弛度。3.我们还发现了人类研究中报告的大鼠踝关节松弛度的性别差异。腓肠肌的伸展性和连接蛋白亚型组成也存在差异。4.大鼠腓肠肌的一次延长收缩试验性地降低了大鼠踝关节的灵活性并增加了大鼠腓肠肌的伸展性。我们还证实，暴露的腓肠肌的被动张力显着高于未治疗的对照组。两组的肌肉湿重相同，表明不存在水肿。有趣的是，这种现象只在年轻大鼠中出现。5.我们研究了大鼠腓肠肌重复离心运动（20天）对踝关节僵硬度和肌联蛋白（connectin）亚型组成的影响。长时间离心运动后，腓肠肌内侧肌湿重显着增加。肌球蛋白-ATP酶染色显示IIB型纤维的百分比减少，而IIA型纤维的百分比增加。我们发现偏心运动组的踝关节僵硬度明显小于假手术等长训练组。最重要的是，我们得出的结论是，长期离心运动会增加肌肉力量和关节松弛。我们现在认为，长期离心运动具有特殊性，应该有助于调节和预防运动相关损伤。较少的

项目成果

Effect of eccentric joint flexion on stiffness of rat ankle joint and gastrocnemius muscle extensibility.

偏心关节屈曲对大鼠踝关节刚度和腓肠肌伸展性的影响。

• 发表时间: 2003
• 期刊: Medicine & Science in Sports & Exercise. 35(5)Supplement1
• 作者: Ochi;E;Song;H S.;Nakazato;K;Nakajima;H
• 通讯作者: H

Effect of increased excursion of the ankle on the severity of acute eccentric contraction-induced strain injury in the gastrocnemius - An in vivo rat study

• DOI: 10.1177/0363546503262199
• 发表时间: 2004-07-01
• 期刊: AMERICAN JOURNAL OF SPORTS MEDICINE
• 影响因子: 4.8
• 作者: Song, H;Nakazato, K;Nakajima, H
• 通讯作者: Nakajima, H

EFFECT OF ECCENTRIC JOINT FLEXION ON STIFFNESS OF RAT ANKLE JOINT AND GASTROCEMIUS MUSCLE EXTENSIBILITY.

偏心关节屈曲对大鼠踝关节刚度和腓肠肌伸展性的影响。

• 发表时间: 2003
• 期刊: Medicine & Science in Sports & Exercise 35.5
• 作者: Ochi;E;Song;H;Nakazato;K;Nakajima,H
• 通讯作者: Nakajima,H

Song H: "Effect of Increased Excursion of the Ankle on the Severity of Acute Eccentric Contraction-Induced Strain Injury in the Gastrocnemius : An In Vivo Rat Study"American Journal of Sports Medicine. 32(In press). (2004)

Song H：“踝关节偏移增加对腓肠肌急性偏心收缩引起的应变损伤严重程度的影响：一项体内大鼠研究”美国运动医学杂志。

Eccentric Training Causes Muscular Hypertrophy, Fiber-type Transformation and Interleuikin-6 Production in the Rat Gastrocnemius Muscle

离心训练导致大鼠腓肠肌肌肉肥大、纤维型转化和白介素 6 产生

• 发表时间: 2006
• 期刊: Medicine & Science in Sports & Exercise 38.5
• 作者: Ochi;E;Nakazato;K;Ishii;N
• 通讯作者: N