Effects of static magnetic field given by the iron-platinum magnet alloy on osteoanagenesis

本研究属于动物试验，检查磁性铂铁的生物相容性和骨相容性。将非磁性和磁性铂-铁、钛和不锈钢植入大鼠胫骨中1 - 12周。并对骨生长速度、骨成熟度和骨生长量进行了分析，研究了静磁场对成骨的影响。结果表明，钛、非磁性和磁性铂铁不会影响组织病理学、植入物周围区域的Ca和P分布。Ca/P指数和细胞生长量随时间变化无统计学意义。从这个实验中，根据静态磁场，成骨作用没有得到证实。但静磁场对体内骨组织无损伤，但与不锈钢相比，骨生长量明显增加。从这些发现来看，非磁性和磁性铂-铁在骨成熟和骨生长方面与钛相同，在生物相容性和骨相容性方面优于钛，从而表明磁性合金在体内使用是安全的。

This research pertains to animal trials examining the bio-compatibility and bone-compatibility of magnetic platinum-iron. Non-magnetic and magnetic platinum-iron, titanium, and stainless steel were implanted into the tibial of rats between 1 and 12 weeks. Furthermore, bone growth speed, bone maturation and bone growth quantity were analyzed and the influence of the static magnetic field on osteogenesis was studied. The findings were that titanium, non-magnetic and magnetic platinum iron did not affect the histopathology, the distribution of Ca and P in the areas surrounding the Implant. What is more, over time the Ca/P index and cells growth quantity showed no statistical change. From this experiment, according to the static magnetic field, osteogenesis was not proven. However, there was no in vivo damage by the static magnetic field, but compared to stainless steel bone growth quantity was significant. From these findings, non-magnetic and magnetic platinum-iron were the same as titanium on bone maturation and bone growth, excelling at bio-compatibility and bone-compatibility, in turn suggesting the safe use of magnetic alloy in vivo.