Effects of static magnetic field given by the iron-platinum magnet alloy on osteoanagenesis

这项研究是关于检测磁性铂铁的生物相容性和骨相容性的动物试验。将非磁性和磁性铂铁、钛和不锈钢植入1~12周大鼠的胫骨内。此外，还分析了骨生长速度、骨成熟度和骨生长量，并研究了恒磁场对成骨的影响。结果表明，钛、非磁性和磁性铂铁对种植体周围区的组织病理学、钙磷分布无影响。此外，随着时间的推移，Ca/P指数和细胞生长量无统计学变化。从这个实验来看，根据静磁场，成骨并没有得到证实。然而，静磁场对体内没有损伤，但与不锈钢相比，骨生长量显著。从这些发现，非磁性和磁性铂铁在骨成熟和骨生长方面与钛相同，在生物相容性和骨相容性方面优于钛，这反过来表明磁性合金在体内的使用是安全的。

This research pertains to animal trials examining the bio-compatibility and bone-compatibility of magnetic platinum-iron. Non-magnetic and magnetic platinum-iron, titanium, and stainless steel were implanted into the tibial of rats between 1 and 12 weeks. Furthermore, bone growth speed, bone maturation and bone growth quantity were analyzed and the influence of the static magnetic field on osteogenesis was studied. The findings were that titanium, non-magnetic and magnetic platinum iron did not affect the histopathology, the distribution of Ca and P in the areas surrounding the Implant. What is more, over time the Ca/P index and cells growth quantity showed no statistical change. From this experiment, according to the static magnetic field, osteogenesis was not proven. However, there was no in vivo damage by the static magnetic field, but compared to stainless steel bone growth quantity was significant. From these findings, non-magnetic and magnetic platinum-iron were the same as titanium on bone maturation and bone growth, excelling at bio-compatibility and bone-compatibility, in turn suggesting the safe use of magnetic alloy in vivo.