Trafficking of DNA between chloroplast and nucleus in higher plants

高等植物叶绿体和细胞核之间 DNA 的运输

• 批准号: DP0345500
• 负责人: Prof Jeremy Timmis
• 金额: $ 9.32万
• 依托单位: The University of Adelaide
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2003
• 资助国家: 澳大利亚
• 起止时间: 2003-01-01 至 2005-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP0345500
• 关键词: Trafficking; DNA; between; chloroplast; nucleus

Reliably high levels of diverse proteins can be produced in plant chloroplasts. Environmental risks are considered low for chloroplast genes because they are not transmitted by pollen. However, we recently discovered that DNA escapes from the tobacco chloroplast to the nucleus with unexpectedly high frequency. The associated environmental risks require immediate investigation. This project will determine the fate of chloroplast DNA that has moved to the nuclear genome and gain insight into the evolutionary and environmental consequences of chloroplast DNA escape. The ubiquity of DNA escape also will be studied in an edible crop with a small genome, tomato.

植物叶绿体中可以可靠地产生高水平的多种蛋白质。叶绿体基因的环境风险被认为很低，因为它们不通过花粉传播。然而，我们最近发现DNA从烟草叶绿体逃逸到细胞核的频率出乎意料地高。相关的环境风险需要立即调查。该项目将确定已转移至核基因组的叶绿体 DNA 的命运，并深入了解叶绿体 DNA 逃逸对进化和环境的影响。 DNA 逃逸的普遍性也将在基因组较小的食用作物番茄中进行研究。