Detection of intermolecular force using photoswitchable single molecular tip for chemical identification and manipulation

使用光控单分子尖端检测分子间力以进行化学识别和操作

• 批准号: 16310071
• 负责人: FUKUI Ken-ichi
• 金额: $ 9.86万
• 依托单位: Tokyo Institute of Technology
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B)
• 财政年份: 2004
• 资助国家: 日本
• 起止时间: 2004 至 2006
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-16310071/
• 关键词: Molecular tip; Chemical identification; Scanning Probe Microscopy; Chemical interaction; photoisomerization; hydrogen bonding; マニピュレーション; 非接触原子間力顕微鏡; Noncontact AFM

We have designed and synthesized a tripodal single molecule which can be used as a prove tip and whose function is controllable by light irradiation for chemical identification of surface species. The molecule consists of rigid tripod part to be fixed on the Au-coated cantilever by formation of three Au-S bonds and a functional group that specifically interacts with target molecules. These two parts are connected by azobenzene moiety that shows reversible photo-isomerization to the cis-form by UV light (360 nm) and the trans-form by visible light (450 nm) irradiation. With this special molecular tip combined with the frequency-modulation detection atomic force microscopy (FM-AFM) technique, one can image exactly the same area by two kinds of tips (the trans-tip senses the surfaces with the functional group and the cis-tip traces the surface topography), which has a great advantage to extract the chemical interaction from the total interactions working between the tip and sample. Reversible photo-switching of the tripod molecule adsorbed on an Au-coated cantilever and imaging of a surface by the single molecule have been achieved. With a tip molecule that has carboxyl group (-COOH) on its head, total interaction increased with a trans-tip at the sites of OH species on TiO_2(110), where hydrogen bonding interaction is possible.

我们设计并合成了一个三脚架结构的单分子，它可以作为一个探针，其功能可以通过光照射来控制，用于表面物种的化学鉴定。该分子由刚性三脚架部分组成，通过形成三个Au-S键和一个与靶分子特异性相互作用的官能团固定在Au涂层悬臂梁上。这两个部分通过偶氮苯部分连接，该偶氮苯部分通过UV光（360 nm）显示可逆的光异构化为顺式，通过可见光（450 nm）照射显示可逆的光异构化为反式。这种特殊的分子探针与调频检测原子力显微镜（FM-AFM）技术相结合，可以实现两种探针（反式探针用于检测表面官能团，顺式探针用于跟踪表面形貌）对同一区域的成像，从而可以从探针与样品之间的相互作用中提取化学作用。三脚架分子吸附在Au涂层的悬臂梁和成像的表面上的可逆的光开关已被实现。在TiO_2（110）表面的OH物种位置上，当尖端分子的头部带有羧基（-COOH）时，总的相互作用随着反式尖端的增加而增加，在那里氢键相互作用是可能的。

项目成果

Control of probe function in noncontact atomic force microscopy using photo-responsive molecular tip

使用光响应分子尖端控制非接触原子力显微镜中的探针功能

• 发表时间: 2006
• 期刊: e-Journal of Surface Science and Nanotechnology 4
• 作者: D.Takamatsu;Y.Yamakoshi;K.Fukui
• 通讯作者: K.Fukui

In situ STM study of potential-dependent height change of a tetrathiafulvalene derivative embedded in alkanethiol self-assembled monolayers on Au(111).

• DOI: 10.1021/jp0558472
• 发表时间: 2005-11
• 期刊: The journal of physical chemistry. B
• 作者: Y. Yokota;A. Miyazaki;K. Fukui;T. Enoki;M. Hara

Dynamic and Collective Electrochemical Responses of Tetrathiafulvalene Derivative Self-Assembled Monolayers

四硫富瓦烯衍生物自组装单层膜的动态和集体电化学响应

• 发表时间: 2006
• 期刊: Journal of Physical Chemistry B 110
• 作者: Y.Yokota;A.Miyazaki;K.Fukui;T.Enoki;K.Tamada;M.Hara
• 通讯作者: M.Hara

実践ナノテクノロジー 走査プローブ顕微鏡と局所分光

实用纳米技术：扫描探针显微镜和局部光谱学

• 发表时间: 2005
• 作者: 福井賢一;岩澤康裕
• 通讯作者: 岩澤康裕

Strong Intermolecular Electronic Coupling within a Tetratiafulvalene Island Embedded in Self-Assembled Monolayers

嵌入自组装单分子层中的四富瓦烯岛内的强分子间电子耦合

• 发表时间: 2007
• 期刊: Journal of American Chemical Society (印刷中)
• 作者: Y.Yokota;K.Fukui;T.Enoki;M.Hara
• 通讯作者: M.Hara