Oral health and subsequent risk of lifestyle-related diseases : a cohort study in Japanese dentists

口腔健康和随之而来的生活方式相关疾病的风险：日本牙医的队列研究

基本信息

批准号：
16390189
负责人：
WAKAI Kenji
金额：
$ 9.31万
依托单位：
Nagoya University (2006-2007)Aichi Cancer Center Research Institute (2004-2005)
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (B)
财政年份：
2004
资助国家：
日本
起止时间：
2004 至 2007
项目状态：
已结题

项目摘要

To elucidate the relevance of oral health with subsequent risk of lifestyle-related diseases, we are conducting a cohort study in Japanese dentists. The information on oral status could be collected with a self-administered questionnaire from the participants, and they have been followed-up through their affiliated dental associations. In this project, we examined the correlates of tooth loss and the association between tooth loss and nutrient intake in a cross-sectional study utilizing the baseline data In addition, the associations of tooth loss with the total mortality and the incidence of stroke and ischemic heart diseases were assessed by analyzing the cohort data. A total of 21,272 dentists (mean age ± SD, 522 ± 12.3 years ; women, 8.0%) participated in this study Age, female sex, smoking, history of diabetes, and systolic blood pressure were positively correlated with the risk of tooth loss (≧5 teeth) while use of floss, frequency of sealing, and vigorous exercise were inversely linked to the risk The adjusted geometric means in nutrient intakes were higher among those with more present teeth except for carbohydrate. The significantly increased risk of total death (age and sex-adjusted mortality rate ratio, 1.3-1.6) was found in relation to the loss of more than five teeth compared with that of less than five. Although the adjustment for confounding factors attenuated this association, the higher mortality rate ratio was still observed in those with more tooth loss. The age and sex-adjusted risk of incident stroke was also correlated with the number of lost teeth, but the correlation was attenuated after adjustment for other confounders. Although a further follow-up is warranted, this study suggests the bilateral association between oral health and general wellbeing.

为了阐明口腔健康与随后与生活方式相关疾病的风险的相关性，我们正在日本牙医进行一项队列研究。可以通过参与者的自我管理调查表收集有关口头状况的信息，并通过其会员牙科协会进行了跟进。在该项目中，我们研究了利用基线数据的横截面研究中牙齿脱落的相关性以及牙齿脱落和营养摄入之间的关联，通过分析队列数据来评估牙齿丧失与总死亡率以及中风和缺血性心脏病的事件的关联。共有21,272名牙医（平均年龄±SD，522±12.3岁；妇女，8.0％）参加了这项研究年龄，女性性别，性别，吸烟，糖尿病病史和收缩压呈正相关，与牙齿丧失的风险（5齿）相关，同时使用较高的造成较高的牙齿，而有力地播放了较高的频率，并且在使用的频率上，往来的频率是相关的，并且在密封的频率上互相互动，同时又有链接的频率，同时又有链接的范围，同时又有链接的范围。那些除碳水化合物以外的牙齿的人。与五颗牙齿的损失相比，发现总死亡的风险显着增加（年龄和性别调整的死亡率比例为1.3-1.6）。尽管对混杂因素的调整减弱了这种关联，但在牙齿脱落更多的人中仍观察到较高的死亡率比率。发生事件中风的年龄和性别调整的风险也与牙齿失去的数量相关，但是在调整其他混杂因素后，相关性减弱了。尽管有必要进一步的随访，但这项研究表明口腔健康与一般福祉之间的双边关联。

项目成果

期刊论文数量（15）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

A questionnaire survey on use of gloves and latex allergy in dentists : findings from the Fukuoka Dental Association Health Study

关于牙医使用手套和乳胶过敏的问卷调查：福冈牙科协会健康研究的结果

DOI：
发表时间：
2004
期刊：
影响因子：
0
作者：
Naito;T;Dusopp;J;Honda;S;Furusawa;M;Yokota;M
通讯作者：
M

The associations of oral health-related quality of life with psycho-logical distress and general health among Japanese.

日本人口腔健康相关生活质量与心理困扰和总体健康状况的关系。

DOI：
发表时间：
2007
期刊：
影响因子：
0
作者：
Wakai;K;Naito;M;Naito;T;Kojima;M;Nakagaki;H;Umemura;O;Yokota;M;Hanada;N;Kawamura;T;内藤徹;Naito M
通讯作者：
Naito M

A cohort study on oral health, general wellbeing, and nutrition among dentists : aiming to provide evidence from dental practicians

一项关于牙医口腔健康、总体健康和营养的队列研究：旨在提供牙科医师的证据

DOI：
发表时间：
2005
期刊：
Journal of Japan Dental Association 58
影响因子：
0
作者：
Wakai;K;Kawamura;T;Naito;M;Naito;T;Kojirna;M;Nakagaki;H;Umemura;O;Yokota;M;Hanada;N
通讯作者：
N

歯科医師を対象とした歯と全身の健康、栄養との関連に関するコホート研究-歯科医師自身からのエビデンス発信をめざして-

关于牙齿、一般健康和牙医营养之间关系的队列研究 - 旨在传播牙医本身的证据 -