Development of Computeraided Diagnosis System for Evaluation of Regional Pulmonary Blood Flow by use of Different Thee Phase of MDCT Images

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The outline of our research results is summarized to the following four items :1. Regional Pulmonary Blood Flow AnalysisWe have developed a subtraction algorithm for evaluation of pulmonary blood flow abnormalities based on non-solid registration algorithm by use of enhanced and non-enhanced MDCT images. We have developed an extraction algorithm of peripheral pulmonary vessels from volume MDCT data. Our algorithm is useful for diagnosis of diffuse lung diseases. We have also developed a detection algorithm of acute pulmonary embolisms.2. Function Analysis of Pulmonary RespirationCOPD is one of targets for function analysis of pulmonary respiration. For the diagnosis of COPD, we have developed a radial measurement of bronchus. And also, for the evaluation of emphysema, we have developed an algorithm of lobar segmentation. Moreover, we have developed a measurement algorithm of displacements for ribs and diaphragms by use of inspiratory and expiratioy MDDCT images.3. Analysis of Diffuse Lung DiseaseDiffuse lung disease is one of targets for our study. We have developed an algorithm of diffuse lung analysis for whole lungs obtained from MDCT volume data. In our algorithm, whole lungs are diagnosed as one of seven diffuse lung disease patterns.4. Analysis of Auscultation SoundsFor evaluation of pulmonary diseases, such as pneumonia and COPD, we have developed an algorithm of auscultation sounds. We have achieved more than 90% recognition rate for differentiation of auscultation sounds.