Cyclophane Carbene Complexes as Catalysts: An Integrated Synthetic, Structural, and Mechanistic Approach

环芳卡宾配合物作为催化剂：综合合成、结构和机理方法

• 批准号: DP0344334
• 负责人: Prof Murray Baker
• 金额: $ 17.8万
• 依托单位: The University of Western Australia
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2003
• 资助国家: 澳大利亚
• 起止时间: 2003-06-27 至 2006-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP0344334
• 关键词: Cyclophane; Carbene; Complexes; Catalysts; Integrated

Metal-carbene complexes are emerging as efficient catalysts for chemical processes of immense importance to the pharmaceutical and fine chemicals industries. This project will build on the recent discovery of a family of complexes that exhibits the highest activity yet reported for metal-carbene catalysts in carbon-carbon bond-forming reactions. Insights into the ways the new catalysts work will be gained through a combination of synthetic, mechanistic, and structural studies. This detailed investigation of structure/reactivity relationships will provide an understanding of why these catalyst are so efficient and hence give synthetic leads for the development of superior new catalysts suitable for industrial application.

金属-卡宾配合物是新兴的高效催化剂，用于对制药和精细化学品工业极其重要的化学过程。该项目将建立在最近发现的一系列络合物的基础上，这些络合物在碳-碳键形成反应中表现出金属-卡宾催化剂的最高活性。深入了解新催化剂的工作方式将通过合成，机理和结构研究的组合获得。对结构/反应性关系的详细研究将有助于了解这些催化剂为何如此有效，从而为开发适合工业应用的上级新催化剂提供合成线索。