Effects of New Photodynamic Therapy to Testicular Tumor Cells

新型光动力疗法对睾丸肿瘤细胞的影响

• 批准号: 17591682
• 负责人: KAMANO Hiroshi
• 金额: $ 2.44万
• 依托单位: Kagawa University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2005
• 资助国家: 日本
• 起止时间: 2005 至 2008
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-17591682/
• 关键词: ewphotodynamictherapy; metalloporphyrin; 新光線力学療法; 新光線力学; 培養細胞

新光線力学療法とは, 新しい光感受性物質13, 17-bis(1-carboxypropionyl) carbamoylethyl-3, 8-bis(1-decanyloxyethyl)-2, 7, 12, 18 tetramethyl-porphyrinato gallium, 又は, 誘導体を細胞に取り込ませ, 可視光線照射を行い, 細胞に変化を誘導する方法である。細胞に光感受性物質を添加し, 翌日, 光感受性物質を除去, 可視光線を照射し, 培養持続した。新しい光感受性物質の構造式の違いにより効果に差があることを見いだした。

New light mechanical method, new light receptive substance 13, 17-bis (1-carboxypropionyl) carbamoylethyl-3, 8-bis (1-decanyloxyethyl)-2, 7, 12, 18 tetramethyl-porphyrinato gallium, and the cell size of the cell can be used to illuminate the line of light, and the cell will guide the method of radiation. The photoreceptor was added to the cell, and the next day, the photoreceptor was removed, and the light was irradiated. The new photosensitive material is not suitable for the production of photoreceptor.

项目成果

13, 17-BIS(1-CARBOXYPROPIONYL)CARBAMOYLETHYL-3, 8-BIS(1-DECANYLOXYETHYL)-2, 7, 12, 18-TETRAMETHYL-PORPHYRINATO GALLIUM (III) INDUCED THE DECREMENT OF THE HUMAN LEUKEMIA CELLS PROLIFERATION

13、17-二(1-羧基丙酰)氨基甲酰基-3、8-二(1-癸氧乙基)-2、7、12、18-四甲基-卟啉镓(III)诱导人白血病细胞增殖减少

• 发表时间: 2006
• 作者: Kamano H;Kubota Y;Tanaka T;Okamato K;Sakata I
• 通讯作者: Sakata I

13, 17-BIS(1-CARBOXYPROPIONYL)CARBAMOYLETHYL-3, 8-BIS(1-DECANYL0XYETHYL)-2, 7, 12, 18-TETRAMETHYL -PORPHYRINATO GALLIUM(III)TO THE TESTICULAR TUMOR AND OTHER CELLS

13, 17-二(1-羧基丙酰基)氨基甲酰基-3, 8-二(1-癸基氧乙基)-2, 7, 12, 18-四甲基-卟啉镓(III)对睾丸肿瘤和其他细胞的作用

• 发表时间: 2009
• 作者: Kamano H;Sakata I
• 通讯作者: Sakata I

13,17-BIS(1-CARBOXYPROPIONYL)CARBAMOYLETHYL-3,8-BIS(1-DECANYLOXYETHYL)-2,7,12,18-TETRAMETHYL-PORPHYRINATO GULLIUM(III) INDUCED THE DECREMENT OF THE HUMAN LEUKEMIA CELLS PROLIFERATION

13,17-二(1-羧基丙酰)氨基甲酰基-3,8-二(1-癸氧乙基)-2,7,12,18-四甲基卟啉铕(III)诱导人白血病细胞增殖减少

• 发表时间: 2006
• 期刊: 28^<th> World Congress of Internal Medicine
• 作者: Kamano H;Kubota Y;Tanaka T;Okamato K;Sakata I
• 通讯作者: Sakata I

13, 17-BIS(1-CARBOXYPROPIONYL) CARBAMOYLETHYL-3, 8-BIS(1-DECANYLOXYETHYL)-2, 7, 12, 18-TETRAMETHYL -PORPHYRINATO GALLIUM (III) TO THE TESTICULAR TUMOR AND OTHER CELLS

13, 17-二(1-羧基丙酰)氨基甲酰基-3, 8-二(1-癸氧乙基)-2, 7, 12, 18-四甲基-卟啉镓 (III) 对睾丸肿瘤和其他细胞的作用

• 发表时间: 2009
• 作者: Kamano H;Sakata I
• 通讯作者: Sakata I