Emergence of cellular intelligence based on selection of various dynamic pattems

基于各种动态模式选择的细胞智能的出现

• 批准号: 18500229
• 负责人: TAKAGI Seiji
• 金额: $ 2.49万
• 依托单位: Hokkaido University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2006
• 资助国家: 日本
• 起止时间: 2006 至 2007
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-18500229/
• 关键词: True slime mould; Physarum; Oscillation pattern; Rotating spiral wave; Locomotive Mechanism; Contemplative behavior; Reaction-diffusion system; Signal integration; 真性粘菌; 振動パターン; 原形質流動; パターン形成; 反応拡散

1. Recognition of the difference in the fractal dimension of a solid surface by the Physarum plasmodium.We investigated rhythmic motions of the plasmodium on an area between fractal and smooth surfaces. Initial synchronous oscillation switched to anti-phase oscillation between the parts of the plasmodium on the fractal and smooth surface areas.2. Emergence of various spatiotemporal patterns of thickness oscillation.The emergence and transitions of various spatiotemporal patterns of thickness oscillation.The emergence and transitions of various spatiotemporal patterns of thickness oscillation were studied in the freshly isolated protoplasm of the Physarum plasmodium. New patterns, such as standing waves, chaotic pattern and rotating spirals, developed successively before the well-documented synchronous pattern appeared.3. Locomotive Mechanism of Physarum PlasmodiaWe investigate how an amoeba mechanically moves its own center of gravity using the model organism Physarum plasmodium. Time- … More dependent velocity fields of protoplasmic streaming over the whole plasmodia were measured with a particle image velocimetry program developed for this work. Combining these data with measurements of the simultaneous movements of the plasmodia revealed a simple physical mechanism of locomotion.4. A new kind of behaviorWe found a new kind of behavior that seems to be 'contemplative' in the Physarum plasmodium. The plasmodium migrating in a narrow lane stops moving for a period of time when it encounters the presence of a chemical repellent. After stopping period, the organism suddenly begins to move again in one of three different ways depending on the repellent concentration, namely penetration, splitting into two fronts and turning back. A model based on reaction-diffusion equations, or Gray-Scott model, succeeds to reproduce the experimental observation.5. Mechanism of signal integrationTo investigate the mechanism of intracellular signal integration, stimulus-responses of the plasmodium were studied at the levels of receptor membrane and cell behavior. Signals of attractants and repellents do not interfere at the receptor level, while avoidance response shifts up to 100 times higher repellent concentration as the attractant concentration increases. We proposed a simple molecular mechanism of information integration which can reproduce the experimental results well. Less

1.利用绒泡菌对固体表面分形维数差异的识别研究了绒泡菌在分形表面和光滑表面之间区域的节律运动。分形表面和光滑表面上的原质团部分由初始的同步振荡转变为反相振荡.不同时空模式的厚度振荡的出现不同时空模式的厚度振荡的出现和转变不同时空模式的厚度振荡的出现和转变在新鲜分离的绒泡菌原生质中进行了研究。在同步斑图出现之前，驻波、混沌斑图和旋转螺旋等新的斑图相继出现.我们以模式生物绒泡菌（Physarum plasmodium）为研究对象，探讨变形虫如何机械地移动自身的重心。时间-- ...更多信息 使用为此工作开发的粒子图像测速程序测量了整个原质团中原生质流的相关速度场。将这些数据与对疟原虫同时运动的测量相结合，揭示了一种简单的运动物理机制。一种新的行为我们发现了一种新的行为，似乎是在绒泡菌疟原虫的“繁殖”。当疟原虫遇到化学驱避剂时，它会在一段时间内停止移动。停止期后，有机体突然开始以三种不同方式之一再次移动，这取决于驱避剂的浓度，即渗透，分裂成两个阵线和回头。一个基于反应扩散方程的模型，即Gray-Scott模型，成功地再现了实验观测.信号整合机制为了探讨胞内信号整合的机制，本研究从受体膜水平和细胞行为水平对疟原虫的刺激反应进行了研究。引诱剂和驱避剂的信号在受体水平上不干扰，而回避反应随着引诱剂浓度的增加而移动高达100倍的驱避剂浓度。我们提出了一个简单的信息整合的分子机制，可以很好地再现实验结果。少

项目成果

Indecisive behavior of amoeba-experiment and mathematical model

阿米巴的犹豫不决行为-实验和数学模型

• 发表时间: 2007
• 作者: S. Takagi;T. Nakagaki;T. Ueda;Y. Nishiura;K.-I. Ueda
• 通讯作者: K.-I. Ueda

真性粘菌の厚み振動が示す多様な動的パターンとパターン間遷移

真实粘菌中厚度振荡所表现出的多种动态模式和模式之间的过渡

• 发表时间: 2007
• 作者: 高木清二;中垣俊之;上田哲男;西浦廉政;上田肇一;高木清二
• 通讯作者: 高木清二

Effects of amount of food on path selection in the transport network of an amoeboid organsim

食物量对变形虫运输网络路径选择的影响

• 发表时间: 2007
• 期刊: Proceedings of Int. Symp. On Topological Aspects of Critical Systems and Networks
• 作者: Toshiyuki Nakagaki;Tetsu Saigusa;Atsusi Tero;Ryo Kobayashi
• 通讯作者: Ryo Kobayashi

Indecisive behavior or amoeba crossing an environmental barrier

优柔寡断的行为或阿米巴原虫跨越环境障碍

• 发表时间: 2007
• 期刊: Proceedings of the international symposium on Topological Aspects of Critical Systems and Networks
• 作者: S. Takagi;Y. Nishiura;T. Nakagaki;T. Ueda;K.-I. Ueda
• 通讯作者: K.-I. Ueda

Wavering Behavior of turue slime mould encountering a competitive stimulation

真实粘菌遇到竞争刺激时的摇摆行为

• 发表时间: 2007
• 作者: Seiji Takagi;Koichi Wako;Tetsuo Ueda
• 通讯作者: Tetsuo Ueda