Development of Chemical Release Controlling Devices for Differentiation Induction of Neural Stem Cells
Development of Chemical Release Controlling Devices for Differentiation Induction of Neural Stem Cells
批准号:
19300161
负责人:
YASUDA Takashi
金额:
$11.9万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2007
资助国家:
日本
项目状态:
已结题
起止时间:
2007 至 2010
中文摘要
研究了神经干细胞诱导分化的化学释放控制技术。首先,在细胞培养室底部制作4个纳米孔阵列和微阀,通过微阀的开关控制纳米孔的化学释放。接下来,在一个腔室下的微通道中产生鞘流,并通过调节形成鞘流的三种流体的流速来控制微孔中的化学物质释放。此外,为了允许在单个设备上释放多种化学物质,在8 × 8的基质中布置了64个腔室,每个腔室的8个微通道都位于一排腔室的正下方。
英文摘要
Techniques of chemical release control for differentiation induction of neural stem cells were developed. First, four nanohole arrays and microvalves were fabricated at the bottom of a cell-culturing chamber, and chemical release from the nanoholes was controlled by switching open/close of the microvalves. Next, a sheathflow was generated in a microchannel under a chamber, and chemical release from microholes was controlled by regulating flow rates of three fluids which form the sheathflow. Moreover, in order to permit multiple chemicals to be released on a single device, 64 chambers were arranged in an 8 x 8 matrix, and each of 8 microchannels was located directly under a row of chambers.
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シースフローと微小孔を用いた薬剤放出制御デバイス
利用鞘流和微孔的药物释放控制装置
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[H.Sakai, A.Sato, S.Takeoka, E.Tsuchida, 河本真弥]
通讯作者:
河本真弥
マイクロ流体デバイスによる培養細胞の局所的化学刺激
使用微流体装置对培养细胞进行局部化学刺激
DOI:
--
发表时间:
2010
期刊:
日本機械学会誌 Vol.113
影响因子:
--
作者:
[M.Yamaguchi, et al., 安田隆]
通讯作者:
安田隆
バイオMEMSによる微量生体試料の操作・刺激・計測
使用 BioMEMS 对微小生物样本进行操作、刺激和测量
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[K.Taguchi, et al., 安田隆]
通讯作者:
安田隆
再生医療に向けた細胞刺激MEMSデバイス-微小孔とマイクロ流路を用いた神経幹細胞の薬剤刺激技術-
用于再生医学的细胞刺激MEMS装置 - 利用微孔和微通道的神经干细胞药物刺激技术 -
DOI:
--
发表时间:
2010
期刊:
光アライアンス
影响因子:
--
作者:
[H.Sakai, H.Horinouchi, K.Kobayashi, E.Tsuchida, 安田隆]
通讯作者:
安田隆
DOI:
10.1016/j.sna.2007.05.035
发表时间:
2007-09-12
期刊:
SENSORS AND ACTUATORS A-PHYSICAL
影响因子:
4.6
作者:
[Nakashima, Yuta, Yasuda, Takashi]
通讯作者:
Yasuda, Takashi
共 12 条
Analysis of membrane protein function using extracellular vesicles and microhole devices
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批准号:20K21903
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项目类别:Grant-in-Aid for Challenging Research (Exploratory)
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资助金额:$4.16万
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财政年份:2020
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负责人:YASUDA Takashi
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依托单位:
Co-culture and Extracellular Potential Measurement Using Microhole and Microelectrode Arrays
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批准号:16H03171
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.15万
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财政年份:2016
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负责人:YASUDA Takashi
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依托单位:
Technique for function analysis of membrane transport proteins using cell-derived liposomes
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批准号:25560204
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.5万
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财政年份:2013
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负责人:YASUDA Takashi
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依托单位:
A study on prevention method of soft tissue damage of oral mucosa during under the long-term respiratory care in ICU.
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批准号:25862167
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$2.5万
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财政年份:2013
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负责人:YASUDA Takashi
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依托单位:
Prediction of maximum possible storm surges and damages induced by global warming in Tokyo, Ise and Osaka bays of Japan
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批准号:24360199
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.23万
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财政年份:2012
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负责人:YASUDA Takashi
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依托单位:
Development of a method with high-reliability to forecast the occurrence of location and time of local heavy rainfall within 24 hours.
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批准号:23656304
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.58万
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财政年份:2011
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负责人:YASUDA Takashi
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依托单位:
Development of a Blood Testing Device Using DNA-templated Nanowires
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批准号:23300168
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.73万
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财政年份:2011
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负责人:YASUDA Takashi
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依托单位:
After Bourdius death, the study of the development of the school and the controversial context in the Bourdieus theory.
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批准号:22530510
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.25万
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财政年份:2010
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负责人:YASUDA Takashi
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依托单位:
Development of biosensing technology using cell-derived liposomes
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批准号:22650105
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.1万
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财政年份:2010
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负责人:YASUDA Takashi
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依托单位:
Evaluation of typhoon intensity affected by global warming and development of a prediction system of the typhoon power for the strategy and countermeasure to reduce the disaster
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批准号:21360234
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$7.99万
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财政年份:2009
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负责人:YASUDA Takashi
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依托单位:
Fabrication of p-type ZnO using hydroge co-doping
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批准号:20560014
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.0万
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财政年份:2008
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负责人:YASUDA Takashi
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依托单位:
Development of air-sea-land coupled model for storm surge forecast and its application into scientific examination on possible maximum storm surge
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批准号:18360236
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$10.53万
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财政年份:2006
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负责人:YASUDA Takashi
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依托单位:
Verification and modeling of the sea-surface bursting layer toward a new paradigm of wind-induced currents - strong-wind driven currents -
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批准号:16360243
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$4.22万
-
财政年份:2004
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负责人:YASUDA Takashi
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依托单位:
Development of a Microfluidic System for Neuronal Differentiation Control
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批准号:16300158
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$8.32万
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财政年份:2004
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负责人:YASUDA Takashi
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依托单位:
Study on wave forecasting and hindcasting method based on air-wave-sea coupled model adaptable for open sea boundary
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批准号:13555141
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$5.7万
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财政年份:2001
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负责人:YASUDA Takashi
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依托单位:
Sensory-Hair-Based Flow Sensor
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批准号:13450101
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$10.56万
-
财政年份:2001
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负责人:YASUDA Takashi
-
依托单位:
Development of the sea-surface bursting layer model for microscopic evaluation of wind wave breaker effects on currents
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批准号:12650509
-
项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.69万
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财政年份:2000
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负责人:YASUDA Takashi
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依托单位:
Development of an Air Flow Microsensor and Its Application to a Flow Control System
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批准号:11450099
-
项目类别:Grant-in-Aid for Scientific Research (B).
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资助金额:$8.77万
-
财政年份:1999
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负责人:YASUDA Takashi
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依托单位:
STUDY OF EXCITONIC PROPETIES OF LOW-DIMENSINAL ZnO
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批准号:10650024
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$0.64万
-
财政年份:1998
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负责人:YASUDA Takashi
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依托单位:
Explanation and modelling of the mechanism of generation and development of breaking wave jet
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批准号:10650501
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.92万
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财政年份:1998
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负责人:YASUDA Takashi
-
依托单位:
海外基金