Stabilization mechanism of collagen helix by using host-guest model peptides
Stabilization mechanism of collagen helix by using host-guest model peptides
批准号:
19350059
负责人:
OKUYAMA Kenji
金额:
$10.23万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2007
资助国家:
日本
项目状态:
已结题
起止时间:
2007 至 2009
中文摘要
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英文摘要
Understanding the mechanism of the stabilization and destabilization of a collagen helix induced by Hyp residues is one of important issues in structural study of collagen. The present study has revealed the rule for ring puckering of Hyp residues, which governs stabilization and destabilization of collagen helix, by the high resolution structure analyses of collagen-model peptides.
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水溶液中における(Pro-Pro-Gly)10の三重らせんー1本鎖転移挙動
(Pro-Pro-Gly)10在水溶液中的三螺旋-单链转变行为
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[喜田裕介, 寺尾憲, 奥山健二]
通讯作者:
奥山健二
The structure analysis of the collagen-model peptide, (Pro-Pro-Gly) 4-Hyp-Asp-Gly-(Pro-Pro-Gly) 4 crystal
胶原蛋白模型肽 (Pro-Pro-Gly) 4-Hyp-Asp-Gly-(Pro-Pro-Gly) 4 晶体的结构分析
DOI:
--
发表时间:
2007
期刊:
影响因子:
--
作者:
[Kawaguchi, T.]
通讯作者:
T.
Comment on Microfibrillar structure of type 1 collagen in situ by Orgel et al. (2006), Proc. Natl Acad. Sci. USA, 103, 9001-9005
Orgel 等人对 1 型胶原原位微纤维结构的评论。
DOI:
--
发表时间:
2009
期刊:
Acta Cryst. D65
影响因子:
--
作者:
[F.Tanaka, T.Koga, H.Kojima, F.M.Winnik, K.Okuyama]
通讯作者:
K.Okuyama
Chain dimension and hydration behavior of collagen model peptides in aqueous solution: [Glycyl-4(R)-Hydroxyprolyl-4(R)-Hydroxyproline]n and [Glycyl-Prolyl-4(R)-Hydroxyproline]n
胶原蛋白模型肽在水溶液中的链尺寸和水合行为:[Glycyl-4(R)-Hydroxyprolyl-4(R)-Hydroxyproline]n 和 [Glycyl-Prolyl-4(R)-Hydroxyproline]n
DOI:
--
发表时间:
2008
期刊:
Macromolecules 41
影响因子:
--
作者:
[K. Terao, K. Mizuno, M. Murashima, Y. Kita, C. Hongo, K. Okuyama, T. Norisue, H.P. Bachinger]
通讯作者:
H.P. Bachinger
The structural analysis of the collagen-model peptide, (Pro-Pro-Gly)4- Hyp-Asp-Gly-(Pro-Pro-Gly)4 crystal
胶原蛋白模型肽 (Pro-Pro-Gly)4-Hyp-Asp-Gly-(Pro-Pro-Gly)4 晶体的结构分析
DOI:
--
发表时间:
2007
期刊:
影响因子:
--
作者:
[T. Kawaguchi, M. Shimura, C. Hongo, K. Noguchi, K. Okuyama, K. Mizuno, H.P. Bachinger]
通讯作者:
H.P. Bachinger
共 35 条
Verification of Okuyama Model for Collagen based on Single Crystal Analyses of Model Peptides at High Resolution
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批准号:16550107
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.3万
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财政年份:2004
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负责人:OKUYAMA Kenji
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依托单位:
Verification of Okuyama model for native collagen based on X-ray diffraction pattern obtained by synchrotron radiation
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批准号:11650922
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.24万
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财政年份:1999
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负责人:OKUYAMA Kenji
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依托单位:
X-ray structure analysis system for fibrous polymers using imaging plate and GUI
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批准号:10555329
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$2.88万
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财政年份:1998
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负责人:OKUYAMA Kenji
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依托单位:
Development of Structure Analysis System of Crystalline Polymers by using an Imaging Plate
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批准号:07455380
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$4.16万
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财政年份:1995
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负责人:OKUYAMA Kenji
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依托单位:
Self-Organization of Bilayr-Forming Crystals
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批准号:04680053
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.15万
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财政年份:1992
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负责人:OKUYAMA Kenji
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依托单位:
Structural Investigation of Silk I Form Prepared from Crystalline Fraction of Silk Fibroin
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批准号:61560062
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.54万
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财政年份:1986
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负责人:OKUYAMA Kenji
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依托单位:
海外基金