Fluid mechanical study on the roles of the endothelial surface glycocalyx

在血管内皮细胞表面存在蛋白多糖和糖蛋白的纤维基质层，并且已经广泛研究了该层的生理作用。在本研究中，我们研究了溶质和溶剂的跨层传输和对血细胞的影响，从流体力学的角度来看。目前的分析表明，该层起着重要的作用，作为一个分子过滤器，并指出显着的电荷的输运性质的影响。

The presence of fiber matrix layer of proteoglycans and glycoproteins at the surface of vascular endothelial cells has been reported and physiological roles of the layer have been investigated extensively. In the present study, we studied the transport of solute and solvent across the layer and the effect on blood cells, from fluid mechanical point of view. The present analysis has suggested that the layer plays an important role as a molecular filter and indicated significance effects of electric charge on the transport property.