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Development of rapid and simultaneous diagnosis and therapy for musculoskeletal sarcomas using acridine orange excited by high-power flash light

Development of rapid and simultaneous diagnosis and therapy for musculoskeletal sarcomas using acridine orange excited by high-power flash light
使用高功率闪光灯激发吖啶橙快速同步诊断和治疗肌肉骨骼肉瘤的进展
批准号:
19390390
负责人:
KUSUZAKI Katsuyuki
金额:
$10.82万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2007
资助国家:
日本
项目状态:
已结题
起止时间:
2007 至 2009

项目摘要

项目成果

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中文摘要
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英文摘要
To develop photodynamic diagnosis and photodynamic therapy using acridine orange excited by high-power flash light provided from xenon lamp in musculoskeletal sarcomas, we performed this study using mouse osteosarcoma model. Results showed that it was possible to brilliantly detect tumor localization through skin by PDD and to strongly inhibit tumor growth by PDT after intravenous AO injection followed by flash light illumination.
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会议论文
Novel Hyperthermia for MetastaticBone Tumors with Magnetic Materials
利用磁性材料治疗转移性骨肿瘤的新型热疗
DOI: --
发表时间: 2008
期刊:
影响因子: --
作者: [Matsumine A, Kusuzaki K, Nakamura T,Niimi R, Nakazora S, Matsubara T,Satonaka H, Uchida A]
通讯作者: Uchida A
Acridine orange could be an innovative anticancer agent under photon energy
吖啶橙可能是光子能量下的创新抗癌剂
DOI: --
发表时间: 2007
期刊: In Vivo 21
影响因子: --
作者: [Kusuzaki K, et. al.]
通讯作者: et. al.
Extracorporeal photodynamic image detection of mouse osteosarcoma in soft tissues utilizing fluorovisualization effect of acridine orange.
利用吖啶橙荧光可视化效应对小鼠软组织骨肉瘤进行体外光动力图像检测。
DOI: --
发表时间: 2006
期刊: Oncology 70(6)
影响因子: --
作者: [Satonaka H., et al.]
通讯作者: et al.
Extracorporeal Photodynamin Image Detection of Mouse Osteosarcoma in Soft Tissue Utilizing Fluorovisualizatiom Effect of Acridine Orange
利用吖啶橙荧光可视化作用进行体外光动力图像检测小鼠软组织骨肉瘤
DOI: --
发表时间: 2007
期刊:
影响因子: --
作者: [Satonaka H, Kusuzaki K, et. al.]
通讯作者: et. al.
22
    Challenging study of immunotherapy for osteosarcoma usingmicroparticles induced by photodynamic therapy
    • 批准号:
      23659730
    • 项目类别:
      Grant-in-Aid for Challenging Exploratory Research
    • 资助金额:
      $2.33万
    • 财政年份:
      2011
    • 负责人:
      KUSUZAKI Katsuyuki
    • 依托单位:
    Development of photodynamic and radiodynamic therapy with acridine orange for new limb salvage surgery in musculoskeletal sarcomas
    • 批准号:
      14207058
    • 项目类别:
      Grant-in-Aid for Scientific Research (A)
    • 资助金额:
      $16.06万
    • 财政年份:
      2002
    • 负责人:
      KUSUZAKI Katsuyuki
    • 依托单位:
    Development of a new surgical strategy in tumor resection for malignant bone and soft tissue tumors with cytocidal effect of acridine orange excited by various dynamic energy-wave.
    • 批准号:
      12470312
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $6.72万
    • 财政年份:
      2000
    • 负责人:
      KUSUZAKI Katsuyuki
    • 依托单位:
    Basic research on cell-biological feature of multidrug resistant osteosarcoma and overcoming of resistance
    • 批准号:
      07457340
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $4.8万
    • 财政年份:
      1995
    • 负责人:
      KUSUZAKI Katsuyuki
    • 依托单位:
    海外基金