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Polymorphism in drug resistant genes of Plasmodium falciparum

Polymorphism in drug resistant genes of Plasmodium falciparum
恶性疟原虫耐药基因多态性
批准号:
19406011
负责人:
UEMURA Haruki
金额:
$9.73万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2007
资助国家:
日本
项目状态:
已结题
起止时间:
2007 至 2009

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中文摘要
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英文摘要
Due to the wide spread of resistant malaria parasites to commonly used anti-malarial drugs, ACTs (Artemisinin-based Combination Therapies) are recommended as the first line treatment therapies in many malaria countries. From the comparison of polymorphisms in Plasmodium falciparum genotypes, we observed a tendency of decreasing mutant alleles of pfcrt and pfmdr 1 genes in Vietnam parasites. We assume it would be effect of introduction and usage of artemisinin and its derivatives in this country.
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DOI: --
发表时间: 2009
期刊:
影响因子: --
作者: [P Xiao, O Usami, Y Suzuki, H Ling, N Shimizu, H Hoshino, M Zhuand, Y Ashino, H Gu, T Hattori, 五十棲理恵]
通讯作者: 五十棲理恵
DOI: 10.1128/jcm.01449-09
发表时间: 2010-01-01
期刊: JOURNAL OF CLINICAL MICROBIOLOGY
影响因子: 9.4
作者: [Isozumi, Rie, Uemura, Haruki, Nakazawa, Shusuke]
通讯作者: Nakazawa, Shusuke
Polymorphism in pfcrt and pfmdr1 genes of malaria parasite populations in Binh Phuoc, Vietnam.
越南平福疟原虫种群 pfcrt 和 pfmdr1 基因多态性。
DOI: --
发表时间: 2008
期刊:
影响因子: --
作者: [Wada K, Arimatsu M, Higashi T, Yoshikawa T, Oda S, Taniguchi H, Kawashima M, Aizawa Y, 高田伸弘, 松村紀明・中島洋一, H. Uemura]
通讯作者: H. Uemura
Polymorphism in pfcrt and pfmdrl genes of malaria parasite populations in Binh Phuoc, Vietnam
越南平福疟原虫种群 pfcrt 和 pfmdrl 基因多态性
DOI: --
发表时间: 2008
期刊:
影响因子: --
作者: [Uemura H., et al]
通讯作者: et al
8
    Efficiency of ACT on malaria treatments and analysis of polymorphisms in drug resistance genes of Plasmodium falciparum
    • 批准号:
      16H05817
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $11.32万
    • 财政年份:
      2016
    • 负责人:
      UEMURA Haruki
    • 依托单位:
    Screening of T. cruzi trans-sialidase inhibitors for a therapeutic agent of Chagas disease
    • 批准号:
      26460508
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $3.24万
    • 财政年份:
      2014
    • 负责人:
      UEMURA Haruki
    • 依托单位:
    Drug resistant genes of Plasmodium falciparum: Characteristic polymorphisms in each malaria endemic countries
    • 批准号:
      22406010
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $11.56万
    • 财政年份:
      2010
    • 负责人:
      UEMURA Haruki
    • 依托单位:
    Polymorphism in pfcrt and pfmdr1 genes of malaria parasite populations in South-East countries
    • 批准号:
      14406003
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $4.22万
    • 财政年份:
      2002
    • 负责人:
      UEMURA Haruki
    • 依托单位:
    海外基金