Polymorphism in drug resistant genes of Plasmodium falciparum
Polymorphism in drug resistant genes of Plasmodium falciparum
批准号:
19406011
负责人:
UEMURA Haruki
金额:
$9.73万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2007
资助国家:
日本
项目状态:
已结题
起止时间:
2007 至 2009
中文摘要
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英文摘要
Due to the wide spread of resistant malaria parasites to commonly used anti-malarial drugs, ACTs (Artemisinin-based Combination Therapies) are recommended as the first line treatment therapies in many malaria countries. From the comparison of polymorphisms in Plasmodium falciparum genotypes, we observed a tendency of decreasing mutant alleles of pfcrt and pfmdr 1 genes in Vietnam parasites. We assume it would be effect of introduction and usage of artemisinin and its derivatives in this country.
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ベトナムBinh Phuoc省で採取された熱帯熱マラリア原虫の縦断的網羅的薬剤耐性遺伝子解析(pfcrt, pfmdr 1)
越南平福省恶性疟原虫耐药基因纵向综合分析(pfcrt、pfmdr 1)
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[P Xiao, O Usami, Y Suzuki, H Ling, N Shimizu, H Hoshino, M Zhuand, Y Ashino, H Gu, T Hattori, 五十棲理恵]
通讯作者:
五十棲理恵
DOI:
10.1128/jcm.01449-09
发表时间:
2010-01-01
期刊:
JOURNAL OF CLINICAL MICROBIOLOGY
影响因子:
9.4
作者:
[Isozumi, Rie, Uemura, Haruki, Nakazawa, Shusuke]
通讯作者:
Nakazawa, Shusuke
Polymorphism in pfcrt and pfmdr1 genes of malaria parasite populations in Binh Phuoc, Vietnam.
越南平福疟原虫种群 pfcrt 和 pfmdr1 基因多态性。
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[Wada K, Arimatsu M, Higashi T, Yoshikawa T, Oda S, Taniguchi H, Kawashima M, Aizawa Y, 高田伸弘, 松村紀明・中島洋一, H. Uemura]
通讯作者:
H. Uemura
Polymorphism in pfcrt and pfmdrl genes of malaria parasite populations in Binh Phuoc, Vietnam
越南平福疟原虫种群 pfcrt 和 pfmdrl 基因多态性
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[Uemura H., et al]
通讯作者:
et al
長崎大学熱帯医学研究所原虫学分野
长崎大学热带医学研究所原生动物学系
DOI:
--
发表时间:
期刊:
影响因子:
--
作者:
[]
通讯作者:
共 8 条
Efficiency of ACT on malaria treatments and analysis of polymorphisms in drug resistance genes of Plasmodium falciparum
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批准号:16H05817
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$11.32万
-
财政年份:2016
-
负责人:UEMURA Haruki
-
依托单位:
Screening of T. cruzi trans-sialidase inhibitors for a therapeutic agent of Chagas disease
-
批准号:26460508
-
项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.24万
-
财政年份:2014
-
负责人:UEMURA Haruki
-
依托单位:
Drug resistant genes of Plasmodium falciparum: Characteristic polymorphisms in each malaria endemic countries
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批准号:22406010
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项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$11.56万
-
财政年份:2010
-
负责人:UEMURA Haruki
-
依托单位:
Polymorphism in pfcrt and pfmdr1 genes of malaria parasite populations in South-East countries
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批准号:14406003
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项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$4.22万
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财政年份:2002
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负责人:UEMURA Haruki
-
依托单位:
Sislic acid recognition proteins of Trypanosoma species
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批准号:11694291
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$2.11万
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财政年份:1999
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负责人:UEMURA Haruki
-
依托单位:
Studies of Trypanosoma cruzi trans-sialidase using transfection method
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批准号:10670232
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.3万
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财政年份:1998
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负责人:UEMURA Haruki
-
依托单位:
A parasite-surface trans-sialidase of Trypanosoma cruzi
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批准号:07670284
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项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$1.54万
-
财政年份:1995
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负责人:UEMURA Haruki
-
依托单位:
A parasite-surface trans-sialidase of Trypanosma family
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批准号:06044183
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项目类别:Grant-in-Aid for international Scientific Research
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资助金额:$3.78万
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财政年份:1994
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负责人:UEMURA Haruki
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依托单位:
海外基金