Drug resistant genes of Plasmodium falciparum: Characteristic polymorphisms in each malaria endemic countries
Drug resistant genes of Plasmodium falciparum: Characteristic polymorphisms in each malaria endemic countries
批准号:
22406010
负责人:
UEMURA Haruki
金额:
$11.56万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2012
中文摘要
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英文摘要
Due to no effective vaccine available for malaria, drug treatment of infected patients are important strategy for malaria control, thus emergence and spread of parasites resistant to commonly used anti-malarials are serious problem. We have analyzed polymorphisms of drug resistant genes of Plasmodium falciparum isolated from Myanmar, Iran, Indonesia and some African countries for obtaining information of drug efficacy and efficiencies. Genotypes of each countries and areas are unique and this indicates appropriate control strategies are required in each countries and areas for efficient malaria control.
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DOI:
10.1371/journal.pone.0023430
发表时间:
2011
期刊:
PloS one
影响因子:
3.7
作者:
[Tsumori Y, Ndounga M, Sunahara T, Hayashida N, Inoue M, Nakazawa S, Casimiro P, Isozumi R, Uemura H, Tanabe K, Kaneko O, Culleton R]
通讯作者:
Culleton R
The efficacy of Dihydroartemisinin and the mutation of 769 codon of PfATPase gene in uncomplicated falciparum malaria in Jayapura District, Papua Province, Indonesia.
双氢青蒿素和 PfATPase 基因 769 密码子突变对印度尼西亚巴布亚省查亚普拉区单纯性恶性疟的疗效。
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[石野智子, 村田英理, 徳永順士, 橘真由美, 坪井敬文, 鳥居本美, Petronella Maria Risamasu]
通讯作者:
Petronella Maria Risamasu
ミャンマーの熱帯熱マラリア原虫薬剤耐性関連遺伝子の多型
缅甸恶性疟原虫耐药相关基因多态性
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[橘真由美, 須藤萌, 横内ゆき, 石野智子, 坪井敬文, 鳥居本美, Hla Myat Mon]
通讯作者:
Hla Myat Mon
Polymorphism of Plasmodium FalciparumDihydrofolate Reductase and Dihydropteroate Synthase Genes among Pregnant Women with Falciparum Malaria in BanjarDistrict, South Kalimantan Province, Indonesia
印度尼西亚南加里曼丹省班贾区恶性疟孕妇恶性疟二氢叶酸还原酶和二氢叶酸合酶基因多态性
DOI:
--
发表时间:
2012
期刊:
Journal of Tropical Life Science
影响因子:
--
作者:
[沼野緑, 長坂葉子, 高木里美, 久米七恵,河野伊保, 山内雄二, 吉田直子, 木村和子, 谷本剛, Fitriah et al.]
通讯作者:
Fitriah et al.
長崎大学熱帯医学研究所原虫学分野
长崎大学热带医学研究所原生动物学系
DOI:
--
发表时间:
期刊:
影响因子:
--
作者:
[]
通讯作者:
共 7 条
Efficiency of ACT on malaria treatments and analysis of polymorphisms in drug resistance genes of Plasmodium falciparum
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批准号:16H05817
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.32万
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财政年份:2016
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负责人:UEMURA Haruki
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依托单位:
Screening of T. cruzi trans-sialidase inhibitors for a therapeutic agent of Chagas disease
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批准号:26460508
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.24万
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财政年份:2014
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负责人:UEMURA Haruki
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依托单位:
Polymorphism in drug resistant genes of Plasmodium falciparum
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批准号:19406011
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$9.73万
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财政年份:2007
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负责人:UEMURA Haruki
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依托单位:
Polymorphism in pfcrt and pfmdr1 genes of malaria parasite populations in South-East countries
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批准号:14406003
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$4.22万
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财政年份:2002
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负责人:UEMURA Haruki
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依托单位:
Sislic acid recognition proteins of Trypanosoma species
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批准号:11694291
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$2.11万
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财政年份:1999
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负责人:UEMURA Haruki
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依托单位:
Studies of Trypanosoma cruzi trans-sialidase using transfection method
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批准号:10670232
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.3万
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财政年份:1998
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负责人:UEMURA Haruki
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依托单位:
A parasite-surface trans-sialidase of Trypanosoma cruzi
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批准号:07670284
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.54万
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财政年份:1995
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负责人:UEMURA Haruki
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依托单位:
A parasite-surface trans-sialidase of Trypanosma family
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批准号:06044183
-
项目类别:Grant-in-Aid for international Scientific Research
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资助金额:$3.78万
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财政年份:1994
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负责人:UEMURA Haruki
-
依托单位:
海外基金