Synthesis of Propellane-Type Heterocycles Using Tandem Cyclization

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Tandem cyclization is a successive intramolecular cyclization when the cyclization is once started, and important for the synthesis of organic cyclization compounds as an efficient synthetic technique. In the research project, the synthesis of novel propellane-type heterocyclic compounds and cyclophane-type macrolides using manganese (III) acetate-based oxidative radical tandem cyclization was studied. The biological activities and physicochemical interests of these compounds are expected.