Analysis of the mechanism of sex determination and gonadal sexual differentiation of the pufferfish, Takifugu rubripes
Analysis of the mechanism of sex determination and gonadal sexual differentiation of the pufferfish, Takifugu rubripes
批准号:
19580207
负责人:
AKIHIKO Yamaguchi
金额:
$3.0万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2007
资助国家:
日本
项目状态:
已结题
起止时间:
2007 至 2009
中文摘要
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英文摘要
In order to assess the involvement of aromatase and sex steroids in gonadal differntiation, an aromatase inhibitor (AI) was administered to developing pufferfish (torafugu) till the 100^<th> day after hatch. AI inhibits ovarian cavity formation, and then irreversible sex change (female to male) was observed. High temperature treatment, which is used for sex reversal of many fishes, induces gonadal degeneration in the pufferfish. We also show that aromatase expression can be regulated by gonadotropin using our newly developed in vitro gonad culture system.
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トラフグ精巣セルトリ細胞の培養系の開発
虎河豚睾丸支持细胞培养体系的建立
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[Rashid H, Lee K-H, Kadomura K, Yamaguchi, A, Matsuyama, M., Rashid H., 重松亨・李敬勲・新居早也佳・Harunur Rashid・山口明彦・松山倫也, 新居早也佳・李敬勲・山日明彦・松山倫也]
通讯作者:
新居早也佳・李敬勲・山日明彦・松山倫也
Effects of exogenous factors on gonadal sex differentiation and development of fugu Talkifugu rubripes
外源因素对红鳍东方鲀性腺性别分化和发育的影响
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[Rashid H, Lee K-H, Kadomura K, Yamaguchi, A, Matsuyama, M., Rashid H.]
通讯作者:
Rashid H.
DOI:
10.1159/000228723
发表时间:
2009-01-01
期刊:
SEXUAL DEVELOPMENT
影响因子:
2.3
作者:
[Lee, K. H., Yamaguchi, A., Matsuyama, M.]
通讯作者:
Matsuyama, M.
(Takifugu rubripes) sexual differentiation: CYP19 regulation and aromatase inhibitor induced testicular development.
(Takifugu rubripes) 性分化:CYP19 调节和芳香酶抑制剂诱导睾丸发育。
DOI:
--
发表时间:
2007
期刊:
Sex. Dev. 1
影响因子:
--
作者:
[Fiashid, H, Kitano H, Lee, KH, Nii, S., Shigematsu, T., Kadomura, K, Yamaguchi, A, Matsuyama, M]
通讯作者:
M
Site-specific mutagenic study of the RS-rich motif in GV-lamin B3 to the identification of involvement of SRPK1 in phosphorylation of p34cdc2 target site in fish oocytes
GV-核纤层蛋白 B3 中富含 RS 基序的位点特异性诱变研究,以鉴定 SRPK1 参与鱼卵母细胞 p34cdc2 靶位点磷酸化的过程
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[山口, 明彦]
通讯作者:
明彦
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