Response mechanism of anti-oxidant enzymes with bacterial infection in fishes-Cell biological approach -
Response mechanism of anti-oxidant enzymes with bacterial infection in fishes-Cell biological approach -
批准号:
19580236
负责人:
OSATOMI Kiyoshi
金额:
$2.91万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2007
资助国家:
日本
项目状态:
已结题
起止时间:
2007 至 2009
中文摘要
在本研究中,我们证明了迟缓爱德华氏菌高毒力株(NUF251)具有阻止巨噬细胞产生活性氧(ROS)的能力,甚至能够在日本比目鱼腹膜巨噬细胞内存活和增殖,而低毒力株(NUF194)则没有这种能力。
英文摘要
In this study, we demonstrated that high virulent strain (NUF251) of Edwardsiella tarda has an ability to prevent the production of reactive oxygen species (ROS) by macrophages, and is even capable of surviving and multiplying within Japanese flounder peritoneal macrophages, where the low virulent strain (NUF194) has no ability.
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Edwardsiella tarda暴露に伴うマクロファージ系細胞株のNO産生及びiNOSの応答
接触迟缓爱德华氏菌后巨噬细胞系中 NO 的产生和 iNOS 反应
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[K. Ishibe, K. Osatomi, K. Hara, K. Kanai, K. Yamaguchi, T. Oda, Keiko Ishibe, 王亜軍]
通讯作者:
王亜軍
DOI:
10.1016/j.fsi.2007.11.001
发表时间:
2008-02-01
期刊:
FISH & SHELLFISH IMMUNOLOGY
影响因子:
4.7
作者:
[Ishibe, Keiko, Osatomi, Kiyoshi, Oda, Tatsuya]
通讯作者:
Oda, Tatsuya
Comparative analysis of the production of nitric oxide (NO) and tumor necrosis factor-α(TNF-α) from macrophages exposed to high virulent and low virulent strains of Edwardsiella tarda.
暴露于高毒力和低毒力爱德华氏菌菌株的巨噬细胞产生一氧化氮(NO)和肿瘤坏死因子-α(TNF-α)的比较分析。
DOI:
--
发表时间:
2009
期刊:
Fish&Shellfish Immunology Vol.27
影响因子:
--
作者:
[K. Ishibe, T. Yamanishi, Y. Wang, K. Osatomi, K. Hara, K. Kanai, K. Yamaguchi, T. Oda]
通讯作者:
T. Oda
Edwardsiella tarda(E. tarda)暴露に伴うヒラメ腹腔マクロファージによる活性酸素種とNOの産生
接触迟缓爱德华氏菌 (E. tarda) 后,鲽鱼腹膜巨噬细胞产生活性氧和一氧化氮
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[K. Ishibe, K. Osatomi, K. Hara, K. Kanai, K. Yamaguchi, T. Oda, Keiko Ishibe, 王亜軍, 王亜軍, 王亜軍, 王 亜軍]
通讯作者:
王 亜軍
魚病細菌感染による培養細胞の活性酸素産生能及びSODの応答
培养细胞活性氧产生能力及SOD对鱼病细菌感染的反应
DOI:
--
发表时间:
2007
期刊:
影响因子:
--
作者:
[K. Ishibe, K. Osatomi, K. Hara, K. Kanai, K. Yamaguchi, T. Oda, Keiko Ishibe, 王亜軍, 王亜軍, 王亜軍, 王 亜軍, 石部恵子]
通讯作者:
石部恵子
共 6 条
Elucidation of the mechanism of evasion of the host immune response by the causative bacteria of Edwardsiellosis in fishes - From the viewpoint of reactive oxygen generation system -
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批准号:20K06228
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.75万
-
财政年份:2020
-
负责人:OSATOMI Kiyoshi
-
依托单位:
Molecular mechanism of the oxidative stress response caused by the anti-oxidant enzyme in fish - Molecular biological approach -
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批准号:17K07940
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.08万
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财政年份:2017
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负责人:OSATOMI Kiyoshi
-
依托单位:
Molecular mechanism of the defense systems against host immunity by causative bacillus of Edwardsiellosis in fishes - Cell biological approach -
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批准号:25450304
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.33万
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财政年份:2013
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负责人:OSATOMI Kiyoshi
-
依托单位:
Mechanism of gene expression regulation of anti-oxidant enzymeswith oxidative stress in fishes - Molecular cell biological approach -
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批准号:22580224
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.91万
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财政年份:2010
-
负责人:OSATOMI Kiyoshi
-
依托单位:
Studies on superoxide dismutase and oxidative stress response in fishes
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批准号:12660186
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.18万
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财政年份:2000
-
负责人:OSATOMI Kiyoshi
-
依托单位:
海外基金